Evidence map›Paper›PMID 26530390›Full record

ReviewNature reviews. Molecular cell biology2015

The expanding world of small RNAs in plants.

Filipe Borges, Robert A Martienssen

Abstract readReview
In one paragraph

Review in Nature reviews. Molecular cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 497 papers.

0numbers the graph read from it
0cells of the map it votes in
497citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

497 citing papers in PubMed.

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  20. TheProceedings of the National Academy of Sciences of the United States of America · 2026
    Article

437 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Filipe BorgesHoward Hughes Medical Institute and Gordon and Betty Moore Foundation, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
Robert A MartienssenHoward Hughes Medical Institute and Gordon and Betty Moore Foundation, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

Funding

Transposons, RNA Interference and HeterochromatinR01GM067014 · NIGMS · COLD SPRING HARBOR LABORATORY · PI MARTIENSSEN, ROBERT A · 2003 to 2016
$4.1M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM067014
6 · The paper itself

Abstract

Plant genomes encode various small RNAs that function in distinct, yet overlapping, genetic and epigenetic silencing pathways. However, the abundance and diversity of small-RNA classes varies among plant species, suggesting coevolution between environmental adaptations and gene-silencing mechanisms. Biogenesis of small RNAs in plants is well understood, but we are just beginning to uncover their intricate regulation and activity. Here, we discuss the biogenesis of plant small RNAs, such as microRNAs, secondary siRNAs and heterochromatic siRNAs, and their diverse cellular and developmental functions, including in reproductive transitions, genomic imprinting and paramutation. We also discuss the diversification of small-RNA-directed silencing pathways through the expansion of RNA-dependent RNA polymerases, DICER proteins and ARGONAUTE proteins.

Indexed as

ArabidopsisArgonaute ProteinsGene Expression Regulation, PlantMicroRNAsRibonuclease IIIRNA-Dependent RNA PolymeraseRNA InterferenceRNA, PlantRNA, Small CytoplasmicRNA, Small InterferingRNA SplicingArgonaute ProteinsMicroRNAsRibonuclease IIIRNA-Dependent RNA PolymeraseRNA, PlantRNA, Small CytoplasmicRNA, Small Interfering

Identifiers

PMID26530390
PMCPMC4948178

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.