Evidence map›Paper›PMID 26530259›Full record

GuidelineJournal of neuro-oncology2015

The role of biopsy in the management of patients with presumed diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline.

Brian T Ragel, Timothy C Ryken, Steven N Kalkanis, Mateo Ziu, Daniel Cahill, Jeffrey J Olson

Abstract readPractice GuidelineSystematic Review
PubMed Publisher
In one paragraph

Guideline in Journal of neuro-oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Guidelines in the management of CNS tumors.Journal of neuro-oncology · 2021
    Guideline
  2. Article
  3. Review
  4. Article
  5. Review
  6. Targeted liquid biopsy for brain tumors.The journal of liquid biopsy · 2024
    Review
  7. Benign Glioma.Advances in experimental medicine and biology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Brian T RagelRebound Orthopedics and Neurosurgery, 200 NE Mother Joseph Place, Suite 210, Vancouver, WA, 98664, USA. brian.ragel@gmail.com.
Timothy C RykenDepartment of Neurosurgery, University of Kansas Medical Center, Kansas City, KS, USA.
Steven N KalkanisDepartment of Neurosurgery, Henry Ford Health System, Detroit, MI, USA.
Mateo ZiuDepartment of Neurosurgery, Seton Brain and Spine Institute, Austin, TX, USA.
Daniel CahillMassachusetts General Hospital, Boston, MA, USA.
Jeffrey J OlsonDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA.
Central Texas Spine Institute · USEmory University · USHenry Ford Health System · USMassachusetts General Hospital · USRebound Orthopedics and Neurosurgery · USUniversity of Kansas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

questionWhat is the optimal role of biopsy in the initial management of presumptive low-grade glioma in adults? TARGET POPULATION: Adult patients with imaging suggestive of a low-grade glioma. RECOMMENDATIONS: LEVEL III: Stereotactic biopsy is recommended when definitive surgical resection is limited by lesions that are deep-seated, not resectable, and/or located within eloquent cortex, or in patients unable to undergo craniotomy due to medical co-morbidities to obtain the critical tissue diagnosis needed for targeted treatment planning for patients with low-grade gliomas. QUESTION: What is the best technique for brain biopsy? TARGET POPULATION: Adult patients with imaging suggestive of a low-grade glioma. RECOMMENDATIONS: LEVEL III: Frameless and frame-based stereotactic brain biopsy for low-grade gliomas are recommended based on clinical circumstances as they provide similar diagnostic yield, diagnostic accuracy, morbidity, and mortality. It is recommended the surgeon consider advanced imaging techniques (e.g., perfusion, spectroscopy, metabolic studies) to target specific regions of interest to potentially improve diagnostic accuracy.

Indexed as

BiopsyBrainBrain NeoplasmsGliomaDisease ManagementEvidence-Based MedicineHumansNeoplasm GradingNeurosurgical ProceduresBiopsyGuidelinesLow-grade gliomaStereotactic biopsy

Identifiers

PMID26530259
OpenAlexW2996483374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.