ArticleBMC cardiovascular disorders2015
Antithrombotic treatment in elderly patients with atrial fibrillation: a practical approach.
Article in BMC cardiovascular disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Elderly Bleeding Risk of Direct Oral Anticoagulants in Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis of Cohort Studies.Drugs in R&D · 2019Pooled it
- Use of dabigatran and rivaroxaban in non-valvular atrial fibrillation: one-year follow-up experience in an Italian centre.Blood transfusion = Trasfusione del sangue · 2018Trial
- Incident thrombocytopenia and bleeding risk in elderly patients with atrial fibrillation on direct oral anticoagulants: insights from the ATHEROsclerosis in Atrial Fibrillation study.Research and practice in thrombosis and haemostasis · 2024Article
- Chinese expert consensus on antithrombotic management of high-risk elderly patients with chronic coronary syndrome.Aging medicine (Milton (N.S.W)) · 2023Article
- The Importance of Appropriate Dosing of Nonvitamin K Antagonist Oral Anticoagulants for Stroke Prevention in Patients with Atrial Fibrillation.TH open : companion journal to thrombosis and haemostasis · 2021Review
- Patterns of Anticoagulation Use in Patients With Cancer With Atrial Fibrillation and/or Atrial Flutter.JACC. CardioOncology · 2020Article
- Thrombocytopenia and Mortality Risk in Patients With Atrial Fibrillation: An Analysis From the START Registry.Journal of the American Heart Association · 2019Article
- Clinical profile and management of rivaroxaban in patients with atrial fibrillation in routine practice in Spain: data from six nationwide studies.Drugs in context · 2019Article
- Influence of frailty on anticoagulant prescription and clinical outcomes after 1-year follow-up in hospitalised older patients with atrial fibrillation.Internal and emergency medicine · 2019Observational
- [Anticoagulation in geriatric patients with atrial fibrillation : With what and for whom no more?]Herz · 2018Review
- Decision Algorithms for Direct Oral Anticoagulant Use in Patients With Nonvalvular Atrial Fibrillation: A Practical Guide for Neurologists.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018Review
- Clinical characteristics and type of antithrombotic treatment in a Spanish cohort of elderly patients with atrial fibrillation according to dependency, frailty and cognitive impairment.Journal of geriatric cardiology : JGC · 2018Article
- Thromboprophylaxis for Patients with High-risk Atrial Fibrillation and Flutter Discharged from the Emergency Department.The western journal of emergency medicine · 2018Article
- Underuse of Anticoagulation in Older Patients with Atrial Fibrillation and CHADSDrugs & aging · 2017Article
- Observational
- Stroke in Older Survivors of Ischemic Stroke: Standard Care or Something Different?Geriatrics (Basel, Switzerland) · 2017Article
- Direct oral anticoagulants in patients with chronic kidney disease: patient selection and special considerations.International journal of nephrology and renovascular disease · 2017Review
- Direct oral anticoagulant use and the incidence of bleeding in the very elderly with atrial fibrillation.Journal of thrombosis and thrombolysis · 2016Article
- Compliance and adherence to oral anticoagulation therapy in elderly patients with atrial fibrillation in the era of direct oral anticoagulants.Journal of geriatric cardiology : JGC · 2016Article
- [New oral anticoagulants for prophylaxis of stroke : Results of an expert conference on practical use in geriatric patients].Zeitschrift fur Gerontologie und Geriatrie · 2016Article
Corrections and comments
- Erratum issuedErratum: Antithrombotic treatment in elderly patients with atrial fibrillation: a practical approach.2015 · Fernández, Suárez [corrected to Suárez Fernández, Carmen]; Rodrigo, Jose Cepeda [corrected to Cepeda Rodrigo, Jose María]; Reino, Pose [corrected to Pose Reino, Antonio]
Authors and funding
12 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtrial fibrillation (AF) in the elderly is a complex condition. It has a direct impact on the underuse of antithrombotic therapy reported in this population. DISCUSSION: All patients aged ≥75 years with AF have an individual yearly risk of stroke >4 %. However, the risk of hemorrhage is also increased. Moreover, in this population it is common the presence of other comorbidities, cognitive disorders, risk of falls and polymedication. This may lead to an underuse of anticoagulant therapy. Direct oral anticoagulants (DOACs) are at least as effective as conventional therapy, but with lesser risk of intracranial hemorrhage. The simplification of treatment with these drugs may be an advantage in patients with cognitive impairment. The great majority of elderly patients with AF should receive anticoagulant therapy, unless an unequivocal contraindication. DOACs may be the drugs of choice in many elderly patients with AF. In this manuscript, the available evidence about the management of anticoagulation in elderly patients with AF is reviewed. In addition, specific practical recommendations about different controversial issues (i.e. patients with anemia, thrombocytopenia, risk of gastrointestinal bleeding, renal dysfunction, cognitive impairment, risk of falls, polymedication, frailty, etc.) are provided.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.