SynthesisBMC anesthesiology2015
Optimal pain management for radical prostatectomy surgery: what is the evidence?
Synthesis in BMC anesthesiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03824808 (A Prospective, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial Evaluating the Use of Perioperative Intravenous Lidocaine Infusion to Decrease Pain Scores and Opioid Consumption After Robotic-Assisted Prostatectomy and Robotic-Assisted Partial Nephrectomy), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial Evaluating the Use of Perioperative Intravenous Lidocaine Infusion to Decrease Pain Scores and Opioid Consumption After Robotic-Assisted Prostatectomy and Robotic-Assisted Partial Nephrectomy
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Efficacy and Harms of Opioid Analgesics for Acute Pain: Overview of Systematic Reviews and Meta-analyses.Drugs · 2026Pooled it
- Impact of analgesic techniques on early quality of recovery after prostatectomy: A 3-arm, randomized trial.European journal of pain (London, England) · 2022Trial
- A Retrospective Cohort Study on the Side Effects of Intrathecal Morphine Administration Combined with General Anaesthesia Versus General Anaesthesia Alone in Prostatectomy Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- An analysis of post-operative pain and narcotic use following robotic assisted laparoscopic prostatectomy for same day discharge.Journal of robotic surgery · 2023Article
- The impact of spinal anaesthesia on perioperative opioid consumption, postoperative pain and oncological outcome in radical retropubic prostatectomy-a retrospective before-and-after effectiveness study.Perioperative medicine (London, England) · 2022Article
- Opioid use after uro-oncologic surgeries in time of opioid crisis.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022Article
- Anaesthetic management for robotic-assisted laparoscopic prostatectomy: the first UK national survey of current practice.Journal of robotic surgery · 2021Article
- Effects of pre-emptive pregabalin and multimodal anesthesia on postoperative opioid requirements in patients undergoing robot-assisted laparoscopic prostatectomy.BMC urology · 2021Article
- Association of surgical approach and prolonged opioid prescriptions in patients undergoing major pelvic cancer procedures.BMC surgery · 2020Article
- Use of a specific questionnaire and perineal electromyography to assess neuropathic pain after radical retropubic prostatectomy.Asian journal of urology · 2019Article
- Application of TAP Block in Laparoscopic Urological Surgery: Current Status and Future Directions.Current urology reports · 2019Review
- Comparison of patient-controlled epidural analgesia with patient-controlled intravenous analgesia for laparoscopic radical prostatectomy.The Korean journal of pain · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncrease in the diagnosis of prostate cancer has increased the incidence of radical prostatectomy. However, the literature assessing pain therapy for this procedure has not been systematically evaluated. Thus, optimal pain therapy for patients undergoing radical prostatectomy remains controversial.
methodsMedline, Embase, and Cochrane Central Register of Controlled Trials were searched for studies assessing the effects of analgesic and anesthetic interventions on pain after radical prostatectomy. All searches were conducted in October 2012 and updated in June 2015.
resultsMost treatments studied improved pain relief and/or reduced opioid requirements. However, there were significant differences in the study designs and the variables evaluated, precluding quantitative analysis and consensus recommendations.
conclusionsThis systematic review reveals that there is a lack of evidence to develop an optimal pain management protocol in patients undergoing radical prostatectomy. Most studies assessed unimodal analgesic approaches rather than a multimodal technique. There is a need for more procedure-specific studies comparing pain and analgesic requirements for open and minimally invasive surgical procedures. Finally, while we wait for appropriate procedure specific evidence from publication of adequate studies assessing optimal pain management after radical prostatectomy, we propose a basic analgesic guideline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.