Evidence map›Paper›PMID 26529473›Full record

ArticleAmerican journal of perinatology2016

Pregnancy Outcomes in Women with 1-Hour Glucose Challenge Test ≥ 200 mg/dL.

Nana-Ama Ankumah, Alan T N Tita, Joseph R Biggio, Lorie M Harper

Abstract read
In one paragraph

Article in American journal of perinatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Nana-Ama AnkumahCenter of Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama.
Alan T N TitaCenter of Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama.
Joseph R BiggioCenter of Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama.
Lorie M HarperCenter of Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama.

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANANDA BASU · 2013 to 2026
$19.5M
OB/GYN FACULTY RESEARCH CAREER DEVELOPMENT PROGRAMK12HD001258 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JENKINS, TODD R · 1999 to 2019
$5.6M
NICHD NIH HHS K12 HD001258NICHD NIH HHS K12HD001258-13NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

objectiveMany protocols diagnose gestational diabetes mellitus (GDM) solely on a 1-hour glucose challenge test (GCT) ≥ 200 mg/dL. However, pregnancy outcomes in these women compared with women diagnosed with a 3-hour glucose tolerance test (GTT) has not been adequately evaluated. We hypothesize that a 1-hour GCT ≥ 200 mg/dL is associated with worse pregnancy outcomes as compared with a GCT 135 to 199 mg/dL with positive GTT. STUDY

designA retrospective cohort of singleton pregnancies complicated by GDM. Maternal outcomes included A2DM, preeclampsia, primary cesarean, and failed trial of labor after cesarean. Perinatal outcomes were large/small for gestational age, shoulder dystocia, and birth injury. Groups were compared with t-test and chi-square test, and logistic regression to adjust for confounders.

resultsA total of 602 women diagnosed with GDM by 1-hour GCT 135 to 199 mg/dL and confirmatory 3-hour GTT (< 200 group) and 225 women diagnosed with 1-hour GCT ≥ 200 alone (≥ 200) were included. The ≥ 200 group had a higher incidence of preeclampsia (16.4 vs. 10.6%) and shoulder dystocia (3.1 vs. 1.0%). Adjusted odds ratio and 95% confidence interval were 1.80 (1.10-2.94) and 5.10 (1.25-20.76), respectively.

conclusionPreeclampsia and shoulder dystocia are more frequent in women with GCT ≥ 200 mg/dL than those with a positive GTT following a GCT of 135 to 199 mg/dL.

Indexed as

AdultBirth InjuriesCesarean SectionCohort StudiesDiabetes, GestationalDystociaFemaleGlucose Tolerance TestHumansHypoglycemic AgentsIncidenceInfant, Small for Gestational AgeInsulinLogistic ModelsOdds RatioPre-EclampsiaHypoglycemic AgentsInsulin

Identifiers

PMID26529473
PMCPMC4863982

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.