ArticleJournal of neurotrauma2016
Mild Traumatic Brain Injury Decreases Broadband Power in Area CA1.
Article in Journal of neurotrauma, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed.
- Article
- Microglia depletion improves hippocampal circuit function after mild traumatic brain injury in male mice.Brain, behavior, and immunity · 2026Article
- High frequency head impact exposure changes hippocampal sharp-wave ripple architecture.PloS one · 2026Article
- Hippocampal interneuronal dysfunction and hyperexcitability in a porcine model of concussion.Communications biology · 2023Article
- Optogenetic Stimulation of CA1 Pyramidal Neurons at Theta Enhances Recognition Memory in Brain Injured Animals.Journal of neurotrauma · 2023Article
- Bumetanide induces post-traumatic microglia-interneuron contact to promote neurogenesis and recovery.Brain : a journal of neurology · 2023Article
- TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.Journal of neuroinflammation · 2022Article
- Peering into the Brain through the Retrosplenial Cortex to Assess Cognitive Function of the Injured Brain.Neurotrauma reports · 2021Article
- The effect of fornix deep brain stimulation in brain diseases.Cellular and molecular life sciences : CMLS · 2020Review
- Mild Traumatic Brain Injury Decreases Spatial Information Content and Reduces Place Field Stability of Hippocampal CA1 Neurons.Journal of neurotrauma · 2020Article
- Neuronal Degeneration Impairs Rhythms Between Connected Microcircuits.Frontiers in computational neuroscience · 2020Article
- Recovery of Theta Frequency Oscillations in Rats Following Lateral Fluid Percussion Corresponds With a Mild Cognitive Phenotype.Frontiers in neurology · 2020Article
- Converging early responses to brain injury pave the road to epileptogenesis.Journal of neuroscience research · 2019Review
- Frequency-Dependent Changes in Resting State Electroencephalogram Functional Networks after Traumatic Brain Injury in Piglets.Journal of neurotrauma · 2019Article
- Deep brain stimulation for the treatment of disorders of consciousness and cognition in traumatic brain injury patients: a review.Neurosurgical focus · 2018Review
- Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
- Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury.The Journal of clinical investigation · 2017Article
- Pathophysiology and Treatment of Memory Dysfunction After Traumatic Brain Injury.Current neurology and neuroscience reports · 2017Review
- Sleep-Wake Disturbances After Traumatic Brain Injury: Synthesis of Human and Animal Studies.Sleep · 2017Review
- Hippocampal Neurophysiologic Changes after Mild Traumatic Brain Injury and Potential Neuromodulation Treatment Approaches.Frontiers in systems neuroscience · 2016Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Cognitive impairment caused by traumatic brain injury (TBI) can lead to devastating consequences for both patients and their families. The underlying neurological basis for TBI-induced cognitive dysfunction remains unknown. However, many lines of research have implicated the hippocampus in the pathophysiology of TBI. In particular, past research has found that theta oscillations, long thought to be the electrophysiological basis of learning and memory, are decreased in the hippocampus post-TBI. Here, we recorded in vivo electrophysiological activity in the hippocampi of 16 mice, 8 of which had previously undergone a TBI. Consistent with previous data, we found that theta power in the hippocampus was decreased in TBI animals compared to sham controls; however, this effect was driven by changes in broadband power and not theta oscillations. This result suggests that broadband fluctuations in the hippocampal local field potential can be used as an electrophysiological surrogate of abnormal neurological activity post-TBI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.