ArticleMolecules (Basel, Switzerland)2015
Optimization of Antifungal Extracts from Ficus hirta Fruits Using Response Surface Methodology and Antifungal Activity Tests.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Optimization of Antifungal Properties of Hop Cone Carbon Dioxide Extracts Based on Response Surface Methodology.Molecules (Basel, Switzerland) · 2024Article
- Pinocembrin-7-Glucoside (P7G) Reduced Postharvest Blue Mold of Navel Orange by SuppressingMicroorganisms · 2020Article
- Antioxidant, Antifungal Activities of EthnobotanicalBiomedicines · 2020Article
- Preservation of Xinyu Tangerines with an Edible Coating Using Ficus hirta Vahl. Fruits Extract-Incorporated Chitosan.Biomolecules · 2019Article
- Inhibitory Effect of 7-Demethoxytylophorine onMicroorganisms · 2019Article
- Inhibition of Key Citrus Postharvest Fungal Strains by Plant Extracts In Vitro and In Vivo: A Review.Plants (Basel, Switzerland) · 2019Review
- Antifungal Activity of Ramulus cinnamomi Explored by ¹H-NMR Based Metabolomics Approach.Molecules (Basel, Switzerland) · 2017Article
- Chemical Constituents and Antifungal Activity of Ficus hirta Vahl. Fruits.Plants (Basel, Switzerland) · 2017Article
- Extraction of Natural Antioxidants from the Thelephora ganbajun Mushroom by an Ultrasound-Assisted Extraction Technique and Evaluation of Antiproliferative Activity of the Extract against Human Cancer Cells.International journal of molecular sciences · 2016Article
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6 authors.
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Abstract
The fruits of Ficus hirta (FH) display strong antifungal activity against Penicillium italicum and Penicillium digitatum. In order to optimize the extraction conditions of antifungal extracts from FH fruit, various extraction parameters, such as ethanol concentration, extraction time, solvent to solid ratio and temperature, were chosen to identify their effects on the diameters of inhibition zones (DIZs) against these two Penicillium molds. Response surface methodology (RSM) was applied to obtain the optimal combination of these parameters. Results showed that the optimal extraction parameters for maximum antifungal activity were: 90% (v/v) ethanol concentration, 65 min extraction time, 31 mL/g solvent to solid ratio and 51 °C temperature. Under the abovementioned extraction conditions, the experimental DIZs values obtained experimentally were 57.17 ± 0.75 and 39.33 ± 0.82 mm, which were very close to the values of 57.26 and 39.29 mm predicted by the model. Further, nine kinds of phytopathogens were tested in vitro to explore the antifungal activity of the FH extracts. It was found for the first time that the FH extracts showed significant inhibition on the growth of P. italicum, A. citri, P. vexans, P. cytosporella and P. digitatum.
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