ReviewFrontiers in surgery2015
Treatment of Fistula-In-Ano with Fistula Plug - a Review Under Special Consideration of the Technique.
Review in Frontiers in surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Evaluation and management of perianal abscess and anal fistula: SICCR position statement.Techniques in coloproctology · 2020Guideline
- Efficacy and safety of autologous platelet-rich plasma in anal fistula: a systematic review and meta-analysis.Annals of Saudi medicinePooled it
- Predictors of recurrence and long-term patient reported outcomes following surgical repair of anal fistula, a retrospective analysis.International journal of colorectal disease · 2024Article
- Current and emerging therapeutic strategies for perianal fistula in Crohn's disease patients.Advances in pharmacology (San Diego, Calif.) · 2024Review
- Effects of an anal fistula plug on anal function after surgery for treatment of a trans-sphincteric anal fistula.Langenbeck's archives of surgery · 2021Observational
- Sphincter-saving therapy for fistula-in-ano: long-term follow-up after FiLaCTechniques in coloproctology · 2021Article
- Long-Term Clinical Results of Use of an Anal Fistula Plug for Treatment of Low Trans-Sphincteric Anal Fistulas.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Five years of experience with the FiLaC™ laser for fistula-in-ano management: long-term follow-up from a single institution.Techniques in coloproctology · 2017Article
- Short-term outcomes of a novel endoscopic clipping device for closure of the internal opening in 100 anorectal fistulas.Techniques in coloproctology · 2016Article
- An experience with video-assisted anal fistula treatment (VAAFT) with new insights into the treatment of anal fistulae.Techniques in coloproctology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn a recent Cochrane review, the authors concluded that there is an urgent need for well-powered, well-conducted randomized controlled trials comparing various modes of treatment of fistula-in-ano. Ten randomized controlled trials were available for analyses: There were no significant differences in recurrence rates or incontinence rates in any of the studied comparisons. The following article reviews the studies available for treatment of fistula-in-ano with a fistula plug with special attention paid to the technique. MATERIAL AND
methodsPubMed, Medline, Embase, and the Cochrane medical database were searched up to July 2015. Sixty-four articles were relevant for this review.
resultsHealing rates of 50-60% can be expected for treatment of complex anal fistula with a fistula plug, with a plug-extrusion rate of 10-20%. Such results can be achieved not only with plugs made of porcine intestinal submucosa but also those made of other biological or synthetic bioabsorbable mesh materials. Important technical steps are firm suturing of the head of the plug in the primary opening and wide drainage of the secondary opening. DISCUSSION: Treatment of a complex fistula-in-ano with a fistula plug is an option with a success rate of 50-60% with low complication rate. Further improvements in technique and better studies are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.