Evidence map›Paper›PMID 26528475›Full record

ReviewFrontiers in bioengineering and biotechnology2015

Enzymes from Extreme Environments and Their Industrial Applications.

Jennifer A Littlechild

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 154 citations in OpenAlex.

  1. Isolation of a lipase-producing strain from yuncheng salt lake and enhancement of lipase activity via UV mutagenesis.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  2. Article
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  4. Review
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  8. A Novel Unorthodox Dimeric Primary Enoyl-CoA Reductase Structure.bioRxiv : the preprint server for biology · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. The outer membrane inApplied and environmental microbiology · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Lipase production fromFrontiers in microbiology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Deciphering the microbial communities of alkaline hot spring in Panamik, Ladakh, India using a high-throughput sequencing approach.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jennifer A LittlechildExeter Biocatalysis Centre, Biosciences, College of Life and Environmental Sciences, University of Exeter , Exeter , UK.
University of Exeter · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

This article will discuss the importance of specific extremophilic enzymes for applications in industrial biotechnology. It will specifically address those enzymes that have applications in the area of biocatalysis. Such enzymes now play an important role in catalyzing a variety of chemical conversions that were previously carried out by traditional chemistry. The biocatalytic process is carried out under mild conditions and with greater specificity. The enzyme process does not result in the toxic waste that is usually produced in a chemical process that would require careful disposal. In this sense, the biocatalytic process is referred to as carrying out "green chemistry" which is considered to be environmentally friendly. Some of the extremophilic enzymes to be discussed have already been developed for industrial processes such as an l-aminoacylase and a γ-lactamase. The industrial applications of other extremophilic enzymes, including transaminases, carbonic anhydrases, dehalogenases, specific esterases, and epoxide hydrolases, are currently being assessed. Specific examples of these industrially important enzymes that have been studied in the authors group will be presented in this review.

Indexed as

carbonic anhydrasedehalogenaseepoxide hydrolaseesterasel-aminoacylasetransaminaseγ-lactamase

Identifiers

PMID26528475
PMCPMC4602302
OpenAlexW2195266629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.