Evidence map›Paper›PMID 26528335›Full record

ArticleArchives of medical science : AMS2015

Aortic valve calcification in 499 consecutive patients referred for computed tomography.

Anna Galas, Tomasz Hryniewiecki, Ilona Michałowska, Cezary Kępka, Elżbieta Abramczuk, Ewa Orłowska-Baranowska, Witold Rużyłło

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anna GalasDepartment of Valvular Heart Disease, Institute of Cardiology, Warsaw, Poland.
Tomasz HryniewieckiDepartment of Valvular Heart Disease, Institute of Cardiology, Warsaw, Poland.
Ilona MichałowskaDepartment of Radiology, Institute of Cardiology, Warsaw, Poland.
Cezary KępkaDepartment of Coronary and Structural Heart Diseases, Institute of Cardiology, Warsaw, Poland.
Elżbieta AbramczukDepartment of Valvular Heart Disease, Institute of Cardiology, Warsaw, Poland.
Ewa Orłowska-BaranowskaDepartment of Valvular Heart Disease, Institute of Cardiology, Warsaw, Poland.
Witold RużyłłoInstitute of Cardiology, Warsaw, Poland.
Institute of Cardiology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAortic valve calcification (AVC) is the most common cause of aortic stenosis. The aim of the study was to assess the prevalence of aortic valve, coronary artery and aortic calcifications and to evaluate the correlation between calcification of the aortic valve, coronary arteries and aorta. MATERIAL AND

methodsThe study included 499 patients aged 60 years and over who underwent coronary computed tomography because of chest pain. Beside coronary artery calcium score (CAC), we evaluated AVC and ascending aorta calcifications (AAC).

resultsAortic valve calcification was found in 144 subjects (28.9% of the whole study population). Prevalence of CAC and AAC was higher than AVC and amounted to 73.8% and 54.0%. Prevalence of AVC, CAC and AAC was significantly lower in the group of patients ≤ 70 years than in the group of patients > 70 years of age (p = 0.0002, p < 0.0001, p < 0.0001). Aortic valve calcification was more often observed in men than women (34.7% vs. 25.4%, p = 0.02). Degree of aortic valve calcification was also significantly higher among men than women (median score 4 vs. 0, p = 0.01). Similar observations were true for CAC and AAC, where both prevalence and degree of calcification was higher among men than women. In the whole study population no correlation was noted between AVC and CAC or AAC (p = 0.34, p = 0.85). There was a significant correlation between AAC and CAC (p < 0.0001).

conclusionsDespite some similarities in pathological mechanism and risk factors, a degenerative defect of the aortic valve could be independent of atheromatous lesions in the coronary arteries and aorta.

Indexed as

aortic valvecalcificationcomputed tomography

Identifiers

PMID26528335
PMCPMC4624733
OpenAlexW2139102687

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.