ArticleFrontiers in behavioral neuroscience2015
Changes in cortical activity associated with adaptive behavior during repeated balance perturbation of unpredictable timing.
Article in Frontiers in behavioral neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02706496 (Age-related Changes in Posture Control and Cortex Activity Under a Dynamic Perturbation), which is not on this map. Cited by 56 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Age-related Changes in Posture Control and Cortex Activity Under a Dynamic Perturbation
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- Transcranial direct current stimulation combined with physical or cognitive training in people with Parkinson's disease: a systematic review.Journal of neuroengineering and rehabilitation · 2020Pooled it
- Effect of transcranial direct current stimulation over the primary motor cortex on short-term balance acquisition in healthy individuals.Journal of neuroengineering and rehabilitation · 2025Trial
- Cortical and neuromuscular features during a side-lying hip abduction drop task are associated with single-leg standing balance.IBRO neuroscience reports · 2026Article
- Higher cortical beta oscillatory power before balance perturbations is associated with worse balance in older adults with Parkinson's Disease, but not in age-matched older adults.bioRxiv : the preprint server for biology · 2026Article
- Cortical responses to balance perturbations persist without active postural control.The Journal of physiology · 2026Article
- A primary central source determines perturbation-evoked N1 amplitudes in younger adults.Journal of neurophysiology · 2026Article
- Cortical activity during preparation and execution of balance recovery behavior in people after mild traumatic brain injury: A preliminary investigation.medRxiv : the preprint server for health sciences · 2026Article
- A Primary Central Source Determines Perturbation-Evoked N1 Amplitudes but not Latencies in Younger Adults.bioRxiv : the preprint server for biology · 2026Article
- Conceptual rethinking of whole-body perturbation-evoked potentials as a biomarker of extralemniscal sensory transmission, alertness and arousal.Frontiers in human neuroscience · 2026Article
- Slower reactive stepping kinematics are associated with lower clinical balance function and delayed cortical evoked responses under challenging balance conditions after stroke.medRxiv : the preprint server for health sciences · 2025Article
- The Neural Contributions to Reactive Balance Control: A Scoping Review of EEG, fNIRS, MRI, and PET Studies.Brain sciences · 2025Review
- Cortical neural activity during responses to mechanical perturbation: Effects of hand preference and hand used.NeuroImage · 2025Article
- Excellent test-retest reliability of perturbation-evoked cortical responses supports feasibility of the balance N1 as a clinical biomarker.Journal of neurophysiology · 2025Article
- The Balance N1 Is Larger in Children With Anxiety and Associated With the Error-Related Negativity.Biological psychiatry global open science · 2025Article
- Task-dependent cross-frequency neural coupling during postural perturbation: insights from EEG-based assessment in elite freestyle aerial skiers.Frontiers in physiology · 2025Article
- Delayed Cortical Responses During Reactive Balance After Stroke Associated With Slower Kinetics and Clinical Balance Dysfunction.Neurorehabilitation and neural repair · 2025Article
- Cross-Task Differences in Frontocentral Cortical Activations for Dynamic Balance in Neurotypical Adults.Sensors (Basel, Switzerland) · 2024Article
- Distinct Cortical Correlates of Perception and Motor Function in Balance Control.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Precise cortical contributions to sensorimotor feedback control during reactive balance.PLoS computational biology · 2024Article
- Delayed cortical engagement associated with balance dysfunction after stroke.medRxiv : the preprint server for health sciences · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The compensation for a sudden balance perturbation, unpracticed and unpredictable in timing and magnitude is accompanied by pronounced postural instability that is suggested to be causal to falls. However, subsequent presentations of an identical perturbation are characterized by a marked decrease of the amplitude of postural reactions; a phenomenon called adaptation or habituation. This study aimed to identify cortical characteristics associated with adaptive behavior during repetitive balance perturbations based on single-trial analyses of the P1 and N1 perturbation-evoked potentials. Thirty-seven young men were exposed to ten transient balance perturbations while balancing on the dominant leg. Thirty two-channel electroencephalography (EEG), surface electromyography (EMG) of the ankle plantar flexor muscles and postural sway (i.e., Euclidean distance of the supporting platform) were recorded simultaneously. The P1 and N1 potentials were localized and the amplitude/latency was analyzed trial by trial. The best match sources for P1 and N1 potentials were located in the parietal (Brodmann area (BA) 5) and midline fronto-central cortex (BA 6), respectively. The amplitude and latency of the P1 potential remained unchanged over trials. In contrast, a significant adaptation of the N1 amplitude was observed. Similar adaptation effects were found with regard to postural sway and ankle plantarflexors EMG activity of the non-dominant (free) leg; i.e., an indicator for reduced muscular co-contraction and/or less temporary bipedal stance to regain stability. Significant but weak correlations were found between N1 amplitude and postural sway as well as EMG activity. These results highlight the important role of the midline fronto-central cortex for adaptive behavior associated with balance control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.