ReviewFrontiers in cellular neuroscience2015
Does non-invasive brain stimulation applied over the dorsolateral prefrontal cortex non-specifically influence mood and emotional processing in healthy individuals?
Review in Frontiers in cellular neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03761303 (Investigation of the Efficacy of Repetitive Transcranial Magnetic Stimulation), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of the Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) as an add-on Therapy in Patients With Post-stroke Depression (PSD)
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evaluating the effects of tDCS on depressive and anxiety symptoms from a transdiagnostic perspective: a systematic review and meta-analysis of randomized controlled trials.Translational psychiatry · 2024Pooled it
- Does non-invasive brain stimulation modulate emotional stress reactivity?Social cognitive and affective neuroscience · 2020Pooled it
- Bifrontal transcranial direct current stimulation modulates fatigue in multiple sclerosis: a randomized sham-controlled study.Journal of neural transmission (Vienna, Austria : 1996) · 2020Trial
- Efficiency of Repetitive Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex in Disorders of Consciousness: A Randomized Sham-Controlled Study.Neural plasticity · 2019Trial
- Frontal Transcranial Direct Current Stimulation Induces Dopamine Release in the Ventral Striatum in Human.Cerebral cortex (New York, N.Y. : 1991) · 2018Trial
- Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN).Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- The effects of prefrontal tDCS and hf-tRNS on the processing of positive and negative emotions evoked by video clips in first- and third-person.Scientific reports · 2024Article
- Treating depression at home with transcranial direct current stimulation: a feasibility study.Frontiers in psychiatry · 2024Article
- Trait-related neural basis of attentional bias to emotions: a tDCS study.Cognitive, affective & behavioral neuroscience · 2023Article
- Implicit IAT Measures and Neurophysiological fNIRS Markers in Response to High-Engagement Advertising.Sensors (Basel, Switzerland) · 2023Article
- How processing emotion affects language control in bilinguals.Brain structure & function · 2023Article
- Editorial: Non-invasive brain stimulation techniques in neurological and neuropsychiatric disorders: Physiological and molecular evidence.Frontiers in systems neuroscience · 2023Article
- Transcranial magnetic stimulation of the brain: What is stimulated? - A consensus and critical position paper.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2022Review
- Dissociating the role of dACC and dlPFC for emotion appraisal and mood regulation using cathodal tDCS.Cognitive, affective & behavioral neuroscience · 2022Article
- Mind the social feedback: effects of tDCS applied to the left DLPFC on psychophysiological responses during the anticipation and reception of social evaluations.Social cognitive and affective neuroscience · 2022Article
- Consumers in the Face of COVID-19-Related Advertising: Threat or Boost Effect?Frontiers in psychology · 2022Article
- Dose-Response Transcranial Electrical Stimulation Study Design: A Well-Controlled Adaptive Seamless Bayesian Method to Illuminate Negative Valence Role in Tinnitus Perception.Frontiers in human neuroscience · 2022Article
- Improvement of Insight with Non-Invasive Brain Stimulation in Patients with Schizophrenia: A Systematic Review.Journal of clinical medicine · 2021Review
- Article
- Effect of Intermittent Theta Burst Stimulation on the Neural Processing of Emotional Stimuli in Healthy Volunteers.Journal of clinical medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dorsolateral prefrontal cortex (DLPFC) is often targeted with non-invasive brain stimulation (NIBS) to modulate in vivo human behaviors. This brain region plays a key role in mood, emotional processing, and attentional processing of emotional information. In this article, we ask the question: when we target the DLPFC with NIBS, do we modulate these processes altogether, non-specifically, or can we modulate them selectively? We thus review articles investigating the effects of NIBS applied over the DLPFC on mood, emotional processing, and attentional processing of emotional stimuli in healthy subjects. We discuss that NIBS over the DLPFC can modulate emotional processing and attentional processing of emotional stimuli, without specifically influencing mood. Indeed, there seems to be a lack of evidence that NIBS over the DLPFC influences mood in healthy individuals. Finally, there appears to be a hemispheric lateralization: when applied over the left DLPFC, NIBS improved processing of positive stimuli and reduced selective attention for stimuli expressing anger, whereas when applied over the right DLPFC, it increased selective attention for stimuli expressing anger.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.