Evidence map›Paper›PMID 26527956›Full record

ArticleClujul medical (1957)2013

The role and prognostic impact of lymph node ratio on stage III colorectal cancer.

Bogdan Micu, Carmen Micu, Daniel-Corneliu Leucuta, Carmen Crivii, Nicolae Constantea

Open access · greenAbstract read
In one paragraph

Article in Clujul medical (1957), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bogdan Micu5 Surgical Clinic, Iuliu Haţieganu University of Medicine and Pharmacy, County Clinic Hospital, Cluj-Napoca, Romania.
Carmen Micu5 Surgical Clinic, Iuliu Haţieganu University of Medicine and Pharmacy, County Clinic Hospital, Cluj-Napoca, Romania ; Department of Anatomy and Embryology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Daniel-Corneliu LeucutaDepartment of Medical Informatics and Biostatistics, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Carmen CriviiDepartment of Anatomy and Embryology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Nicolae Constantea5 Surgical Clinic, Iuliu Haţieganu University of Medicine and Pharmacy, County Clinic Hospital, Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to evaluate the prognostic significance of the lymph node ratio (LNR) in patients with stage III colorectal cancer. MATERIALS AND

methodsWe included 35 stage III colorectal cancer patients who underwent a curative resection at the County Clinic Hospital, Cluj-Napoca, 5(th) Surgical Clinic between January 2006-July2008. Patients were categorized into LNR groups 1 to 5 according to cut-off points: <0.1; 0.21; 0.36; 0.6; >0.61. The Kaplan-Meier and the Cox proportional hazard models were used to evaluate the prognostic effect according to the LNR.

resultsFrom one hundred forty-eight patients who underwent colorectal cancer resection, 33.1 % were stage III and 35 patients met the study inclusion criteria. The five-year survival rate in N1 group was 64.62% compared to the N2 group, where it was 8.57% (p<0.001) The lymph node ratio (LNR) groups consisted of 5 cases (14.2%) in LNR1 group (<0.1), five-year survival rate 100%, 6 cases (17.14%) in LNR2 group (0.11-0.21), five-year survival rate 83.33%, 8 cases (22.8%) in LNR3 group (0.22-0.36), five-year survival rate 37.5%, 12 cases (34.28%) in LNR4 group (0.37-0.60), survival rate 0%, and LNR5 group (>0.6). The relationship between the five-year survival rates in the five LNR groups results in a statistically significant proportionality (p<0.001).

conclusionLymph node ratio can be considered a more accurate and potent modality for prognosis in stage III colorectal cancer and may improve stratification in this heterogenous group of patients.

Indexed as

colorectal cancerlymph nodeprognostic factorstaging

Identifiers

PMID26527956
PMCPMC4462499
OpenAlexW2108752890

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.