Evidence map›Paper›PMID 26527930›Full record

ArticleClujul medical (1957)2013

Assessment of health effects related to fiber glass exposure in fiber glass workers: exhaled biomarkers eCO, FENO and their usefulness in the occupational environment testing.

Bianca Domokos Hancu, Monica Pop

Open access · greenAbstract read
In one paragraph

Article in Clujul medical (1957), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. The value of fractional exhaled nitric oxide in occupational diseases - a systematic review.Journal of occupational medicine and toxicology (London, England) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bianca Domokos HancuPulmonology Department, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Monica PopPulmonology Department, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNumerous epidemiological animal model studies have been conducted in order to assess the health effects of man-made vitreous fibers. They have been shown to be responsible for producing lung fibrosis and lung and peritoneal cancer in animal models. A few large cohort studies were conducted in Europe and the US to assess the health effects of fiber glass in production workers and a higher cancer incidence was evidenced.

aimThe aim of the study is to assess the usefulness of exhaled biomarkers measurements: exhaled nitric oxide and exhaled carbon monoxide in fiber glass workers as indicators of an inflammatory airway response. MATERIAL AND

methodA total of 42 fiber glass workers were included in this study with a minimum of 5 year exposure period in which FENO and eCO values were measured. Also spirometry chest X ray, C reactive protein, fibrinogen, total IgE serum and IL8 serum levels were determined.

resultsIncreased values of exhaled nitric oxide (over 25 ppb) were found in 43% of the fiber glass workers and increased values of exhaled carbon monoxide (over 6 ppm) were determined in 26% of the fiber glass workers. A positive correlation was found between the exposure period and FENO values and total IgE values (p<0.05). A negative correlation coefficient was found between FEF 25-75 predictive values and FENO and total IgE values.

conclusionThese results suggest that exhaled biomarkers can be useful to assess an inflammatory airway response in the occupational environment.

Indexed as

exhaled biomarkersfiber glass

Identifiers

PMID26527930
PMCPMC4462426
OpenAlexW1510331775

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.