Evidence map›Paper›PMID 26527563›Full record

ArticleBritish journal of haematology2016

Selective downregulation of HLA-C and HLA-E in childhood acute lymphoblastic leukaemia.

Sarah B Reusing, Angela R Manser, Jürgen Enczmann, Arend Mulder, Frans H Claas, Mary Carrington, Johannes C Fischer, Arndt Borkhardt, Florian Babor, Markus Uhrberg

Abstract readLetter
In one paragraph

Article in British journal of haematology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Sarah B ReusingInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany.
Angela R ManserInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany.
Jürgen EnczmannInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany.
Arend MulderDepartment of Immunohaematology and Bloodtransfusion, Leiden University Medical Centre, Leiden, the Netherlands.
Frans H ClaasDepartment of Immunohaematology and Bloodtransfusion, Leiden University Medical Centre, Leiden, the Netherlands.
Mary CarringtonCancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Johannes C FischerInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany.
Arndt BorkhardtDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Centre for Child and Adolescent Health, Heinrich Heine University, Düsseldorf, Germany.
Florian BaborDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Centre for Child and Adolescent Health, Heinrich Heine University, Düsseldorf, Germany.
Markus UhrbergInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany. markus.uhrberg@med.uni-duesseldorf.de.
Heinrich Heine University Düsseldorf · DELeiden University · NLRagon Institute of MGH, MIT and Harvard · US

Funding

Effects of genetic polymorphism in MHC, KIR, and related loci on human diseaseZIABC010791 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CARRINGTON, MARY N. · 2009 to 2025
$18.2M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultChild, PreschoolDown-RegulationHistocompatibility Antigens Class IHLA-C AntigensHLA-E AntigensHumansInfantKiller Cells, NaturalPrecursor Cell Lymphoblastic Leukemia-LymphomaReceptors, KIRRNA, MessengerYoung AdultHistocompatibility Antigens Class IHLA-C AntigensHLA-E AntigensReceptors, KIRRNA, MessengerALLchildhood leukaemiaHLA class IKIRNK cells

Identifiers

PMID26527563
PMCPMC4854806
OpenAlexW2157937957

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.