Evidence map›Paper›PMID 26527551›Full record

ArticlePediatrics2015

Obesity and Autism.

Alison Presmanes Hill, Katharine E Zuckerman, Eric Fombonne

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 9 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 9 syntheses or guidelines pooled it, 240 citations in OpenAlex.

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  6. The Prevalence of Diabetes in Autistic Persons: A Systematic Review.Clinical practice and epidemiology in mental health : CP & EMH · 2020
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alison Presmanes HillCenter for Spoken Language Understanding, Institute for Development & Disability, Department of Pediatrics; hillali@ohsu.edu.
Katharine E ZuckermanDivision of General Pediatrics, Doernbecher Children's Hospital; and.
Eric FombonneDepartment of Psychiatry, Institute for Development & Disability, Oregon Health & Science University, Portland Oregon.
Doernbecher Children's Hospital · USOregon Health & Science University · US

Funding

Reducing Barriers to Autism Care in Latino ChildrenK23MH095828 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI ZUCKERMAN, KATHARINE ELIZABETH · 2012 to 2016
$898k
NIMH NIH HHS K23 MH095828NIMH NIH HHS K23MH095828PHS HHS UA3 MC 11054
6 · The paper itself

Abstract

objectiveOverweight and obesity are increasingly prevalent in the general pediatric population. Evidence suggests that children with autism spectrum disorders (ASDs) may be at elevated risk for unhealthy weight. We identify the prevalence of overweight and obesity in a multisite clinical sample of children with ASDs and explore concurrent associations with variables identified as risk factors for unhealthy weight in the general population.

methodsParticipants were 5053 children with confirmed diagnosis of ASD in the Autism Speaks Autism Treatment Network. Measured values for weight and height were used to calculate BMI percentiles; Centers for Disease Control and Prevention criteria for BMI for gender and age were used to define overweight and obesity (≥85th and ≥95th percentiles, respectively).

resultsIn children age 2 to 17 years, 33.6% were overweight and 18% were obese. Compared with a general US population sample, rates of unhealthy weight were significantly higher among children with ASDs ages 2 to 5 years and among those of non-Hispanic white origin. Multivariate analyses revealed that older age, Hispanic or Latino ethnicity, lower parent education levels, and sleep and affective problems were all significant predictors of obesity.

conclusionsOur results indicate that the prevalence of unhealthy weight is significantly greater among children with ASD compared with the general population, with differences present as early as ages 2 to 5 years. Because obesity is more prevalent among older children in the general population, these findings raise the question of whether there are different trajectories of weight gain among children with ASDs, possibly beginning in early childhood.

Indexed as

AdolescentAutism Spectrum DisorderBody Mass IndexBody WeightChildChild, PreschoolFemaleHumansMaleOverweightPediatric ObesityPrevalenceRisk FactorsUnited States

Identifiers

PMID26527551
PMCPMC4657601
OpenAlexW2203075646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.