Evidence map›Paper›PMID 26527471›Full record

ArticleDemography2015

Reproductive History and Later-Life Comorbidity Trajectories: A Medicare-Linked Cohort Study From the Utah Population Database.

Heidi A Hanson, Ken R Smith, Zachary Zimmer

Open access · bronzeAbstract read
In one paragraph

Article in Demography, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Family Size Across the Life Course and Cognitive Decline in Older Mexican Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  4. Article
  5. Article
  6. Familial aggregation of stillbirth: A pedigree analysis of a matched case-control study.BJOG : an international journal of obstetrics and gynaecology · 2023
    Article
  7. Article
  8. Fertility History and Risk of Cognitive Impairment Among Older Parents in the United States.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Article
  9. Article
  10. Article
  11. Early life adversity, reproductive history and breast cancer risk.Evolution, medicine, and public health · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Heidi A HansonDivision of Public Health, University of Utah, 675 Arapeen, Suite 200, Salt Lake City, UT, 84112, USA. Heidi.hanson@hci.utah.edu.
Ken R SmithPopulation Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Zachary ZimmerUniversity of California, San Francisco, San Francisco, CA, USA.
University of Utah · USUniversity of California, San Francisco · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KATHARINE S ULLMAN · 1986 to 2026
$72.6M
The Utah Study of Fertility, Longevity and AgingR01AG022095 · NIA · UNIVERSITY OF UTAH · PI SMITH, KEN R · 2003 to 2015
$9.4M
Modeling Disability Trajectories In Rapidly Aging PopulationsR21AG036938 · NIA · UNIVERSITY OF UTAH · PI ZIMMER, ZACHARY · 2010 to 2011
$375k
NCI NIH HHS P30 CA042014NCI NIH HHS P30 CA42014NIA NIH HHS 1R21AG036938-01NIA NIH HHS 2R01 AG022095NIA NIH HHS R01 AG022095NIA NIH HHS R21 AG036938
6 · The paper itself

Abstract

Reproductive lives of men and women may provide significant insight into later-life morbidity and mortality. Sociological, biological, and evolutionary theories predict a relationship between reproductive history and later-life health; however, current research is lacking consensus on the direction of the relationship. Parity, early age at first birth and last birth, birth weight of offspring, having a child die as an infant, and having a preterm birth may have long-term effects on health for both men and women. In this study, the relationship between these measures of reproductive history and later-life health is examined using the Utah Population Database (a rich source of longitudinal data), and Medicare claims data from 1992-2009. Later-life health is measured using annual Charlson comorbidity index scores, a construct that summarizes most serious illnesses afflicting older individuals. Group-based trajectory modeling that accounts for nonrandom attrition due to death is used to identify the number and types of morbidity trajectories by sex and age for 52,924 individuals aged 65-84 in 1992. For females, early age at first birth, high parity, and having a preterm or high-birth-weight baby are associated with increased risks of comorbidity; later age at last birth is associated with a decreased risk of comorbidity. For males, early age at first birth and having a child with an abnormal birth weight leads to increased risk of comorbidity. The results suggest that both biological and social factors play important roles in the relationships between fertility and morbidity profiles at older ages.

Indexed as

ComorbidityHealth StatusReproductive BehaviorAgedAged, 80 and overCohort StudiesDatabases, FactualFemaleFertilityHumansMaleMedicareParityPregnancyReproductive HealthUnited StatesBiodemographyFertilityHealth trajectoriesLife courseMorbidity

Identifiers

PMID26527471
PMCPMC4655204
OpenAlexW1905641159

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.