Evidence map›Paper›PMID 26526923›Full record

ArticleThe American journal of tropical medicine and hygiene2016

Diagnosis of Opisthorchis viverrini Infection with Handheld Microscopy in Lao People's Democratic Republic.

Isaac I Bogoch, Somphou Sayasone, Youthanavanh Vonghachack, Isabel Meister, Jürg Utzinger, Peter Odermatt, Jason R Andrews, Jennifer Keiser

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. An Epidemiological Survey ofThe American journal of tropical medicine and hygiene · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Isaac I BogochDivisions of Internal Medicine and Infectious Diseases, University Health Network, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; National Institute of Public Health, Ministry of Health, Vientiane, Lao People's Democratic Republic; Faculty of Medical Sciences, University of Health Sciences, Vientiane, Lao People's Democratic Republic; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California isaac.bogoch@uhn.ca.
Somphou SayasoneDivisions of Internal Medicine and Infectious Diseases, University Health Network, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; National Institute of Public Health, Ministry of Health, Vientiane, Lao People's Democratic Republic; Faculty of Medical Sciences, University of Health Sciences, Vientiane, Lao People's Democratic Republic; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California.
Youthanavanh VonghachackDivisions of Internal Medicine and Infectious Diseases, University Health Network, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; National Institute of Public Health, Ministry of Health, Vientiane, Lao People's Democratic Republic; Faculty of Medical Sciences, University of Health Sciences, Vientiane, Lao People's Democratic Republic; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California.
Isabel MeisterDivisions of Internal Medicine and Infectious Diseases, University Health Network, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; National Institute of Public Health, Ministry of Health, Vientiane, Lao People's Democratic Republic; Faculty of Medical Sciences, University of Health Sciences, Vientiane, Lao People's Democratic Republic; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California.
Jürg UtzingerDivisions of Internal Medicine and Infectious Diseases, University Health Network, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; National Institute of Public Health, Ministry of Health, Vientiane, Lao People's Democratic Republic; Faculty of Medical Sciences, University of Health Sciences, Vientiane, Lao People's Democratic Republic; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California.
Peter OdermattDivisions of Internal Medicine and Infectious Diseases, University Health Network, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; National Institute of Public Health, Ministry of Health, Vientiane, Lao People's Democratic Republic; Faculty of Medical Sciences, University of Health Sciences, Vientiane, Lao People's Democratic Republic; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California.
Jason R AndrewsDivisions of Internal Medicine and Infectious Diseases, University Health Network, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; National Institute of Public Health, Ministry of Health, Vientiane, Lao People's Democratic Republic; Faculty of Medical Sciences, University of Health Sciences, Vientiane, Lao People's Democratic Republic; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California.
Jennifer KeiserDivisions of Internal Medicine and Infectious Diseases, University Health Network, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; National Institute of Public Health, Ministry of Health, Vientiane, Lao People's Democratic Republic; Faculty of Medical Sciences, University of Health Sciences, Vientiane, Lao People's Democratic Republic; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California.
Swiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opisthorchiasis is a neglected tropical disease, yet it is of considerable public health importance in Southeast Asia given the predilection for chronically infected persons to develop cholangiocarcinoma. We evaluated a handheld microscope for the diagnosis of Opisthorchis viverrini in a community-based setting in Lao People's Democratic Republic in comparison with conventional light microscopy. In stool samples collected from 104 individuals, handheld microscopy revealed a sensitivity of 70.6% and a specificity of 89.5% for O. viverrini infection. Pearson's correlation for quantitative fecal egg counts between the two devices was 0.98 (95% confidence interval: 0.98-0.99). With small adjustments to further increase diagnostic sensitivity, a handheld microscope may become a helpful tool to screen for O. viverrini and other helminth infections in public health settings.

Indexed as

OpisthorchisAnimalsHumansLaosMicroscopyOpisthorchiasisSensitivity and Specificity

Identifiers

PMID26526923
PMCPMC4710422
OpenAlexW2205146712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.