Evidence map›Paper›PMID 26526885›Full record

ArticleCroatian medical journal2015

Identification and characterization of the highly polymorphic locus D14S739 in the Han Chinese population.

Chengchen Shao, Yaqi Zhang, Yueqin Zhou, Wei Zhu, Hongmei Xu, Zhiping Liu, Qiqun Tang, Yiwen Shen, Jianhui Xie

Open access · diamondAbstract read
In one paragraph

Article in Croatian medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chengchen Shao
Yaqi Zhang
Yueqin Zhou
Wei Zhu
Hongmei Xu
Zhiping Liu
Qiqun Tang
Yiwen Shen
Jianhui XieJianhui Xie, Department of Forensic Medicine, Shanghai Medical College of Fudan University, Shanghai, China, jhxie@fudan.edu.cn.
Shanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo systemically select and evaluate short tandem repeats (STRs) on the chromosome 14 and obtain new STR loci as expanded genotyping markers for forensic application.

methodsSTRs on the chromosome 14 were filtered from Tandem Repeats Database and further selected based on their positions on the chromosome, repeat patterns of the core sequences, sequence homology of the flanking regions, and suitability of flanking regions in primer design. The STR locus with the highest heterozygosity and polymorphism information content (PIC) was selected for further analysis of genetic polymorphism, forensic parameters, and the core sequence.

resultsAmong 26 STR loci selected as candidates, D14S739 had the highest heterozygosity (0.8691) and PIC (0.8432), and showed no deviation from the Hardy-Weinberg equilibrium. 14 alleles were observed, ranging in size from 21 to 34 tetranucleotide units in the core region of (GATA)9-18 (GACA)7-12 GACG (GACA)2 GATA. Paternity testing showed no mutations.

conclusionD14S739 is a highly informative STR locus and could be a suitable genetic marker for forensic applications in the Han Chinese population.

Indexed as

Genetic MarkersMicrosatellite RepeatsPolymorphism, GeneticAllelesAsian PeopleBase SequenceChinaChromosomes, Human, Pair 14DNA PrimersGenetics, PopulationGenotypeHumansMolecular Sequence DataMutationPaternityDNA PrimersGenetic Markers

Identifiers

PMID26526885
PMCPMC4655933
OpenAlexW2099303141

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.