Evidence map›Paper›PMID 26526670›Full record

ReviewJournal of exercise nutrition & biochemistry2015

Effective utilization of genetic information for athletes and coaches: focus on ACTN3 R577X polymorphism.

Naoki Kikuchi, Koichi Nakazato

Open access · greenAbstract readReview
In one paragraph

Review in Journal of exercise nutrition & biochemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Muscular Strength and Quality of Life in Older Adults: The Role ofInternational journal of environmental research and public health · 2021
    Article
  6. Article
  7. Article
  8. Relationships between the Expression of theJournal of human kinetics · 2019
    Article
  9. Review
  10. Article
  11. Article
  12. Frontiers in genetics · 2018
    Review
  13. Article
  14. Frontiers in physiology · 2017
    Review
  15. Exercise genetics: seeking clarity from noise.BMJ open sport & exercise medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Naoki KikuchiSports Training Center, Nippon Sport Science University, Tokyo, Japan.
Koichi NakazatoDepartment of Exercise Physiology, Nippon Sport Science University, Tokyo, Japan.
Nippon Sport Science University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Training variants (type, intensity, and duration of exercise) can be selected according to individual aims and fitness assessment. Recently, various methods of resistance and endurance training have been used for muscle hypertrophy and VO2max improvement. Although several genetic variants are associated with elite athletic performance and muscle phenotypes, genetic background has not been used as variant for physical training. ACTN3 R577X is a well-studied genetic polymorphism. It is the only genotype associated with elite athletic performance in multiple cohorts. This association is strongly supported by mechanistic data from an Actn3-knockout mouse model. In this review, possible guidelines are discussed for effective utilization of ACTN3 R577X polymorphism for physical training.

Indexed as

endurance performanceGenotypemuscle phenotypephysical trainingtrainability

Identifiers

PMID26526670
PMCPMC4624116
OpenAlexW2338098453

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.