ReviewImmunology and cell biology2016
Mechanisms of fate decision and lineage commitment during haematopoiesis.
Review in Immunology and cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- Maternal-fetal dialogue and immunological programming: from fetal development to long-term health outcomes.Frontiers in oncology · 2026Review
- Neutrophil sub-types in maintaining immune homeostasis during steady state, infections and sterile inflammation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023Review
- Neutrophils: Need for Standardized Nomenclature.Frontiers in immunology · 2021Review
- Neutrophil Homeostasis and Emergency Granulopoiesis: The Example of Systemic Juvenile Idiopathic Arthritis.Frontiers in immunology · 2021Review
- Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells.Cell discovery · 2020Article
- Article
- Bone marrow hematopoietic dysfunction in untreated chronic lymphocytic leukemia patients.Leukemia · 2019Article
- Kinetic models of hematopoietic differentiation.Wiley interdisciplinary reviews. Systems biology and medicine · 2019Review
- Stochastic multistationarity in a model of the hematopoietic stem cell differentiation network.Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control · 2018Article
- The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis.Microbiology and molecular biology reviews : MMBR · 2018Review
- Asynchronous lineage priming determines commitment to T cell and B cell lineages in fetal liver.Nature immunology · 2017Article
- More or less-On the influence of labelling strategies to infer cell population dynamics.PloS one · 2017Article
- Cutting-edge single-cell genomics and modelling in immunology.Immunology and cell biology · 2016Article
- Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells.Cell reports · 2016Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Blood stem cells need to both perpetuate themselves (self-renew) and differentiate into all mature blood cells to maintain blood formation throughout life. However, it is unclear how the underlying gene regulatory network maintains this population of self-renewing and differentiating stem cells and how it accommodates the transition from a stem cell to a mature blood cell. Our current knowledge of transcriptomes of various blood cell types has mainly been advanced by population-level analysis. However, a population of seemingly homogenous blood cells may include many distinct cell types with substantially different transcriptomes and abilities to make diverse fate decisions. Therefore, understanding the cell-intrinsic differences between individual cells is necessary for a deeper understanding of the molecular basis of their behaviour. Here we review recent single-cell studies in the haematopoietic system and their contribution to our understanding of the mechanisms governing cell fate choices and lineage commitment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.