Evidence map›Paper›PMID 26526378›Full record

ArticlePaediatrics & child health2015

Clinical characteristics, treatment and outcome of children with Lyme arthritis in Nova Scotia.

Pier Diane Glaude, Adam M Huber, Timothy Mailman, Suzanne Ramsey, Bianca Lang, Elizabeth Stringer

Open access · bronzeAbstract read
In one paragraph

Article in Paediatrics & child health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Child with 3-year history of joint pain and swelling.Canadian family physician Medecin de famille canadien · 2020
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pier Diane GlaudeDepartment of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia.
Adam M HuberDepartment of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia.
Timothy MailmanDepartment of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia.
Suzanne RamseyDepartment of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia.
Bianca LangDepartment of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia.
Elizabeth StringerDepartment of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia.
Dalhousie University · CAIzaak Walton Killam Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLyme disease is an emerging problem in Nova Scotia. Lyme arthritis is a late manifestation of Lyme disease.

objectiveTo describe the demographic characteristics, referral patterns and clinical course of children diagnosed with Lyme arthritis in a tertiary care pediatric rheumatology clinic in Nova Scotia.

methodsIn the present retrospective chart review, subjects diagnosed with Lyme arthritis between 2006 and 2013 were identified through the clinic database. Demographic variables, referral patterns, clinical presentation and information regarding treatment course and outcome were collected.

resultsSeventeen patients were identified; 76% presented in 2012 and 2013. In 37.5% of cases, the referring physician suspected Lyme disease. Most patients presented with one or more painful and/or swollen joints; 94% had knee involvement. Only three of 17 patients had a history of erythema migrans and four of 17 recalled a tick bite. Five patients had a history of neurological manifestations consistent with Lyme disease, although, none had a diagnosis made at the time. Arthritis usually resolved after treatment with standard antibiotics; however, at last follow-up, two patients had antibiotic refractory Lyme arthritis, with one having joint damage despite aggressive arthritis treatment.

conclusionA significant increase in cases of Lyme arthritis has recently been recognized in a pediatric rheumatology clinic in Nova Scotia. A history of a tick bite or erythema migrans were not sensitive markers of Lyme arthritis, and this diagnosis was often not considered by the referring physician. Educational initiatives should be undertaken to increase local awareness of this treatable cause of arthritis in children.

Indexed as

Antibiotic refractoryLyme arthritisLyme diseasePediatrics

Identifiers

PMID26526378
PMCPMC4614091
OpenAlexW1883719699

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.