Evidence map›Paper›PMID 26526159›Full record

ArticleAmerican journal of preventive medicine2016

Influenza Vaccination During Pregnancy: Influenza Seasons 2002-2012, Vaccine Safety Datalink.

Holly C Groom, Michelle L Henninger, Ning Smith, Padma Koppolu, T Craig Cheetham, Jason M Glanz, Simon J Hambidge, Lisa A Jackson, Elyse O Kharbanda, Nicola P Klein and 4 more

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Maternal vaccination-current status, challenges, and opportunities.The journal of obstetrics and gynaecology research · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Influenza and Influenza Vaccine: A Review.Journal of midwifery & women's health · 2021
    Review
  12. Article
  13. Article
  14. Observational
  15. Adherence and Concordance of Influenza and Pertussis Vaccination Coverage in Pregnant Women in Spain.International journal of environmental research and public health · 2019
    Article
  16. Review
  17. Article
  18. Observational
  19. Observational
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Holly C GroomCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon. Electronic address: holly.c.groom@kpchr.org.
Michelle L HenningerCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon.
Ning SmithCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon.
Padma KoppoluCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon.
T Craig CheethamResearch and Evaluation, Kaiser Permanente Southern California, Pasadena, California.
Jason M GlanzInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado.
Simon J HambidgeInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado; Ambulatory Care Services, Denver Health, Denver, Colorado.
Lisa A JacksonGroup Health Research Institute, Seattle, Washington.
Elyse O KharbandaHealthPartners Institute for Education and Research, Minneapolis, Minnesota.
Nicola P KleinKaiser Permanente Vaccine Study Center, Oakland, California.
Natalie L McCarthyImmunization Safety Office, CDC, Atlanta, Georgia.
James D NordinHealthPartners Institute for Education and Research, Minneapolis, Minnesota.
Eric S WeintraubImmunization Safety Office, CDC, Atlanta, Georgia.
Allison L NalewayCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon.

Funding

CDC HHS HHSD200201253584I
6 · The paper itself

Abstract

introductionPregnant women are at risk for influenza-related complications and have been recommended for vaccination by the Advisory Committee on Immunization Practices (ACIP) since 1990. Annual rates of influenza coverage of pregnant women have been consistently low. The Vaccine Safety Datalink was used to assess influenza vaccine coverage over 10 consecutive years (2002-2012); assess patterns related to changes in ACIP recommendations; identify predictors of vaccination; and compare the results with those published by national U.S. surveys.

methodsRetrospective cohort study of 721,898 pregnancies conducted in 2014. Coverage rates were assessed for all pregnancies and for live births only. Multivariate regression analysis identified predictors associated with vaccination.

resultsCoverage increased from 8.8% to 50.9% in 2002-2012. Seasonal coverage rates increased slowly following the 2004 ACIP influenza vaccine recommendation (to remove the first trimester restriction), but spiked significantly during the 2009 H1N1 influenza pandemic. Significant predictors of vaccination during pregnancy included older age; vaccination in a previous season; high-risk conditions in addition to pregnancy; pregnancy during either the 2004-2005 or 2009-2010 seasons; entering the influenza season after the first trimester of pregnancy; and a pregnancy with longer overlap with the influenza season (p<0.001 for each).

conclusionsInfluenza vaccination coverage among pregnant women increased between the 2002-2003 and 2011-2012 seasons, although it was still below the developmental Healthy People 2020 goal of 80%. The 2004 ACIP language change positively impacted first-trimester vaccination uptake. Vaccine Safety Datalink data estimates were consistent with U.S. estimates.

Indexed as

AdultCohort StudiesFemaleHumansInfluenza, HumanInfluenza VaccinesMultivariate AnalysisPregnancyPregnancy Complications, InfectiousRegression AnalysisRetrospective StudiesSeasonsUnited StatesVaccinationInfluenza Vaccines

Identifiers

PMID26526159
PMCPMC13371941

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.