ArticleThe American journal of gastroenterology2015
Colonic Diverticula Are Not Associated With an Increased Risk of Colorectal Adenomas.
Article in The American journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Pooled it
- [Do patients with diverticula have a higher risk of developing polyps and colorectal cancer? Study in a spanish population].Revista espanola de salud publica · 2025Article
- The association between colonic diverticulosis and colorectal polyps in a retrospective cohort study.International journal of colorectal disease · 2025Article
- The connection between diverticulosis and colonic superficial neoplastic lesions in patients who underwent screening colonoscopy.International journal of colorectal disease · 2023Article
- Association of Colonic Diverticula with Colorectal Adenomas and Cancer.Medicina (Kaunas, Lithuania) · 2021Article
- Does Colonic Diverticulosis Raise the Risk of Colorectal Adenoma in Patients with Colorectal Cancer?Gastroenterology research and practice · 2019Article
- An Aberrant Microbiota is not Strongly Associated with Incidental Colonic Diverticulosis.Scientific reports · 2018Article
- Sex differences in risk factors of uncomplicated colonic diverticulosis in a metropolitan area from Northern China.Scientific reports · 2018Article
- Prevalence and characteristics of colonic adenoma in mainland China.Cancer management and research · 2018Article
- Colonic diverticulosis is not a risk factor for colonic adenoma.Therapeutics and clinical risk management · 2018Article
- Low frequency of polyps in colonic regions with diverticulosis.International journal of colorectal disease · 2017Article
- Is early colonoscopy after CT-diagnosed diverticulitis still necessary?International journal of colorectal disease · 2017Observational
- Recent Advances in Diverticular Disease.Current gastroenterology reports · 2016Review
- Association Between Diverticulosis and Colonic Neoplasia: A Meta-Analysis.The American journal of gastroenterology · 2016Article
- Paradigm shift: the Copernican revolution in diverticular disease.Annals of gastroenterologyReview
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectivesPatients with missed colorectal cancer have been reported to be more likely to have colonic diverticulosis. Such an association could be due to either higher risk of neoplasia or difficulty examining the colon in patients with diverticulosis. The aim of this study was to determine whether colonic diverticula are associated with an increased risk for colonic neoplasia.
methodsWe analyzed data from a prospective study of patients undergoing screening colonoscopy that included detailed assessment of all colonic diverticula and colorectal polyps. We used logistic regression to estimate odds ratios and 95% confidence intervals while adjusting for confounding variables.
resultsOur analyses included 624 participants. Of these, 216 (35%) had one or more colorectal adenomas. Diverticula on colonoscopy were not associated with an increased risk of adenomas (odds ratio (OR) 1.0, 95% confidence interval (CI) 0.7-1.4) or advanced adenomas (OR 0.8, 95% CI 0.4-1.5). Those with the greatest burden of diverticula (10 or more) did not have an increased risk of adenomas (OR 1.1, 95% CI 0.7-1.8) compared with no diverticula. Colonic diverticula were not associated with an increased risk of proximal (OR 1.0, 95% CI 0.6-1.6) or distal adenomas (OR 1.0, 95% CI 0.6-1.7).
conclusionsPatients with colonic diverticula do not have an increased risk of colorectal adenomas or advanced adenomas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.