Evidence map›Paper›PMID 26526079›Full record

GuidelineThe American journal of gastroenterology2016

ACG Clinical Guideline: Diagnosis and Management of Barrett's Esophagus.

Nicholas J Shaheen, Gary W Falk, Prasad G Iyer, Lauren B Gerson, American College of Gastroenterology

Erratum issued 3 registry-linked trialsAbstract readPractice Guideline
In one paragraph

Guideline in The American journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 571 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
571citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03191604 completednot on this mapstarted 2017, after this paper: background citation

A Multicenter Study Evaluating the Impact of NBI on Patients With Barrett's Esophagus Associated Neoplasia Undergoing Endoscopic Eradication Therapy (EET)

TypeobservationalSponsorNorthwestern UniversityRan2017 to 2019Enrolled46ConditionsBarrett EsophagusArmsVideo intervention
NCT03814824 nacompletednot on this mapstarted 2019, after this paper: background citation

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS): a Multi-center Randomized Prospective Study

TypeinterventionalSponsorNorthwell HealthRan2019 to 2021Enrolled148ConditionsBarrett's Esophagus Without Dysplasia, Barrett's Esophagus With Dysplasia, Barrett's Esophagus With Low Grade Dysplasia, Barrett's Esophagus With High Grade DysplasiaArmsIRIS (Intelligent real-time image segmentation), VLE (Volumetric laser endomicroscopy)
NCT04054713 nasuspendednot on this mapstarted 2019, after this paper: background citation

Acetic Acid vs Seattle Protocol for Neoplastic Lesions in Barrett Esophagus

TypeinterventionalSponsorCoordinación de Investigación en Salud, MexicoRan2019 to 2025Enrolled76ConditionsBarretts Esophagus With Low Grade Dysplasia, Dysplasia, Intestinal MetaplasiaArmsAcetic acid chromoendoscopy, Seattle protocol
3 · Its place in the literature

Who cites it

571 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Unsedated transnasal endoscopy for the detection of Barrett's esophagus: systematic review and meta-analysis.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023
    Pooled it
  3. AGA Clinical Practice Update on New Technology and Innovation for Surveillance and Screening in Barrett's Esophagus: Expert Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Guideline
  4. Magnitude and Time-Trend Analysis of Postendoscopy Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Article
  10. Advances in the Diagnosis of Barrett's Esophagus.Diagnostics (Basel, Switzerland) · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. High Rates of Dysplasia in a Population-Based Analysis of "Incidental" Barrett's Esophagus.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
  19. Review
  20. Article

511 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Nicholas J ShaheenDivision of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Gary W FalkDivision of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Prasad G IyerDivision of Gastroenterology and Hepatology, Mayo Clinic Minnesota, Rochester, Minnesota, USA.
Lauren B GersonDivision of Gastroenterology, California Pacific Medical Center and Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
American College of Gastroenterology

Funding

Minimally Invasive Molecular Approaches for the Detection of Barrett’s Esophagus and Esophageal AdenocarcinomaR01CA241164 · NCI · MAYO CLINIC ROCHESTER · PI Jagpreet Chhatwal, Prasad G. Iyer · 2019 to 2026
$3.9M
NCI NIH HHS R01 CA241164
6 · The paper itself

Abstract

Barrett's esophagus (BE) is among the most common conditions encountered by the gastroenterologist. In this document, the American College of Gastroenterology updates its guidance for the best practices in caring for these patients. These guidelines continue to endorse screening of high-risk patients for BE; however, routine screening is limited to men with reflux symptoms and multiple other risk factors. Acknowledging recent data on the low risk of malignant progression in patients with nondysplastic BE, endoscopic surveillance intervals are attenuated in this population; patients with nondysplastic BE should undergo endoscopic surveillance no more frequently than every 3-5 years. Neither routine use of biomarker panels nor advanced endoscopic imaging techniques (beyond high-definition endoscopy) is recommended at this time. Endoscopic ablative therapy is recommended for patients with BE and high-grade dysplasia, as well as T1a esophageal adenocarcinoma. Based on recent level 1 evidence, endoscopic ablative therapy is also recommended for patients with BE and low-grade dysplasia, although endoscopic surveillance continues to be an acceptable alternative. Given the relatively common recurrence of BE after ablation, we suggest postablation endoscopic surveillance intervals. Although many of the recommendations provided are based on weak evidence or expert opinion, this document provides a pragmatic framework for the care of the patient with BE.

Indexed as

Barrett EsophagusDecision TreesHumansRisk Factors

Identifiers

PMID26526079
PMCPMC10245082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.