Evidence map›Paper›PMID 26525993›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2015

Physical and Cognitive Activities as Deterrents of Cognitive Decline in a Biracial Population Sample.

Kumar B Rajan, Lisa L Barnes, Kimberly A Skarupski, Carlos F Mendes de Leon, Robert S Wilson, Denis A Evans

Open access · greenAbstract read
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. The importance of modifiable lifestyle factors for episodic memory: a gradient boosted tree analysis.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  4. The Effects of APOE Alleles, Cognitive Activities, and Social Activities on Cognitive Decline in African Americans.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  5. Article
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  10. Article
  11. Lifestyle,Alzheimer's & dementia (Amsterdam, Netherlands)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kumar B RajanRush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL. Electronic address: kumar_rajan@rush.edu.
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL.
Kimberly A SkarupskiCenter on Aging and Health, Department of Medicine, Johns Hopkins University, Baltimore, MD.
Carlos F Mendes de LeonDepartment of Epidemiology, University of Michigan, Ann Arbor, MI.
Robert S WilsonRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL.
Denis A EvansRush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL.
Rush University Medical Center · USJohns Hopkins University · USUniversity of Michigan–Ann Arbor · US

Funding

Risk Factors for Incident Alzheimer's Disease in a Biracial CommunityR01AG011101 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI EVANS, DENIS A · 1993 to 2010
$24.7M
Genetic Epidemiology of Cognitive Decline in an Aging Population SampleR01AG030146 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI EVANS, DENIS A · 2007 to 2018
$6.2M
EPIDEMIOLOGIC STUDY OF PERSONS WITH ALZHEIMERS DISEASER01AG009966 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI EVANS, DENIS A · 1991 to 2009
$5.4M
NIA NIH HHS R01 AG009966NIA NIH HHS R01 AG011101NIA NIH HHS R01 AG030146NIA NIH HHS R01-AG09966NIA NIH HHS R01-AG11101
6 · The paper itself

Abstract

objectivePhysical and cognitive activities are associated with slower cognitive decline. Few studies have examined racial differences in these associations, however. The aim of this study was to examine the association of physical and cognitive activities with level and change in cognitive function among black and white participants. A secondary aim was to explore observed differences between black and white participants using post hoc analyses based on education and cognitive function levels.

methodsData came from a longitudinal study of 7,742 (63% black and 61% female) participants assessed three times over an average of 9.5 years. At baseline, each participant reported number of hours of leisure time physical activity (categorized using quartiles) and rated frequency of participation in cognitively stimulating activities (range: 0-4). A standardized measure of cognition was derived from tests of memory, perceptual speed, and orientation.

resultsOf the 7,742 participants, 2,322 (30%) reported no physical activity. Cognitive decline was slower by about 20% (95% CI: 13%-27%) among whites with physical activity above 1.25 hours compared with those with no physical activity, but showed no significant decrease in cognitive decline relative to those with no physical activity among blacks. Further post hoc analysis revealed cognitive decline to be slower by about 29% (95% CI: 20%-38%) among blacks and whites with higher education and above average baseline cognition. A 1-point increase in cognitive activity frequency decreased cognitive decline by 8% (95% CI: 3%-14%) among blacks and by 14% (95% CI: 7%-20%) among whites.

conclusionsThe benefits of higher physical activity on cognitive decline was observed among whites, and among blacks with higher education and above average baseline cognitive function. Nevertheless, the protective effect of cognitive activity seems to be independent of education and baseline cognitive function among both blacks and whites.

Indexed as

AgedBlack or African AmericanBlack PeopleChicagoCognitionCognition DisordersFemaleFollow-Up StudiesGeriatric AssessmentHumansLongitudinal StudiesMaleMotor ActivityNeuropsychological TestsRisk FactorsWhite Peoplecognitive activitycognitive declineminority healthPhysical activity

Identifiers

PMID26525993
PMCPMC4691548
OpenAlexW1202288383

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.