Evidence map›Paper›PMID 26525885›Full record

ReviewAsian journal of psychiatry2015

Emergent treatments based on the pathophysiology of bipolar disorder: A selective review.

Roscoe O Brady, Matcheri Keshavan

Abstract readReview
In one paragraph

Review in Asian journal of psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Roscoe O BradyDepartment of Psychiatry, Beth-Israel Deaconess Medical Center, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States. Electronic address: robrady@bidmc.harvard.edu.
Matcheri KeshavanDepartment of Psychiatry, Beth-Israel Deaconess Medical Center, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States.

Funding

Longitudinal Imaging Studies in Bipolar DisorderK23MH100623 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BRADY, ROSCOE O. · 2014 to 2018
$883k
NIMH NIH HHS 5 K23 MH100623NIMH NIH HHS K23 MH100623
6 · The paper itself

Abstract

Bipolar disorder is a chronic psychiatric disorder that is a cause of significant symptomatology even in the setting of optimal treatment. Most current treatments are developed from serendipity, and not based on known pathophysiology. In this review we examine a number of somatic and pharmacologic therapies that are poised to become part of the armamentarium of interventions to treat bipolar illness. As a group, these interventions are derived from a growing understanding of the biological underpinnings of bipolar disorders. We will look at emergent treatments based on our understanding of the molecular biology, neuroanatomy, and the genetics of bipolar disorder.

Indexed as

Bipolar DisorderBehavioral SymptomsCalcium Channels, L-TypeHumansPharmacogeneticsPsychosomatic MedicinePsychotropic DrugsCACNA1C protein, humanCalcium Channels, L-TypePsychotropic DrugsBipolar disorderDepressionGeneticsManiaTMS

Identifiers

PMID26525885
PMCPMC4745256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.