Evidence map›Paper›PMID 26525857›Full record

ArticleResearch in social & administrative pharmacy : RSAP

Confirming the theoretical structure of expert-developed text messages to improve adherence to anti-hypertensive medications.

Karen B Farris, Teresa M Salgado, Peter Batra, John D Piette, Satinder Singh, Ahmed Guhad, Sean Newman, Vincent D Marshall, Larry An

Abstract readValidation Study
In one paragraph

Article in Research in social & administrative pharmacy : RSAP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karen B FarrisDepartment of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, USA. Electronic address: kfarris@umich.edu.
Teresa M SalgadoDepartment of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, USA.
Peter BatraDepartment of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, USA.
John D PietteAnn Arbor Department of Veterans Affairs Center for Clinical Management Research, Ann Arbor, USA; University of Michigan School of Public Health, Ann Arbor, USA; University of Michigan School of Medicine, Ann Arbor, USA.
Satinder SinghDivision of Computer Science and Engineering, Department of Electrical Engineering and Computer Science, University of Michigan College of Engineering, Ann Arbor, USA.
Ahmed GuhadUniversity of Michigan College of Pharmacy, Ann Arbor, USA.
Sean NewmanDivision of Computer Science and Engineering, Department of Electrical Engineering and Computer Science, University of Michigan College of Engineering, Ann Arbor, USA.
Vincent D MarshallDepartment of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, USA.
Larry AnDepartment of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, USA.

Funding

Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
NCATS NIH HHS UL1 TR000433NIDDK NIH HHS P30 DK092926
6 · The paper itself

Abstract

backgroundText messages can improve medication adherence and outcomes in several conditions. For this study, experts developed text messages addressing determinants of medication adherence: disease beliefs, medication necessity, medication concerns, and forgetfulness, as well as positive reinforcement messages for patients who were adherent.

objectivesTo validate expert-developed text messages to address medication non-adherence with a group of non-researchers.

methodsA two-wave, card-sorting activity was conducted with students and staff at the University of Michigan. In the first wave, 40 participants grouped 32 messages addressing barriers for medication adherence (disease beliefs, medication necessity, medication concerns, and forgetfulness) according to their perceived relationship. Messages with poor grouping agreement were deleted or modified. In the second wave, positive reinforcement messages were developed and tested along with the previous categories (36 messages) by 37 participants. Similarity and cluster analyses were used to assess agreement between experts and participants.

resultsIn the first card-sorting wave, participants grouped messages into between 2 and 13 separate categories. Similarity analysis showed four groupings of messages, however, some had an agreement below 50% and clusters appeared dispersed. In the second wave, and after messages being edited, participants grouped the messages into between 4 and 9 categories. Five groups (now including positive reinforcement messages) were identified with higher agreement in the similarity and cluster analyses.

conclusionsThe structure of expert-developed text messages to address medication adherence key barriers was confirmed. Messages will be used in future research to determine their impact on affecting medication adherence to anti-hypertensive medications using a reinforcement learning controlled text messaging service.

Indexed as

Reminder SystemsText MessagingAntihypertensive AgentsCluster AnalysisHumansMedication AdherenceReinforcement, PsychologyAntihypertensive AgentsAdherenceCard-sort techniqueMobile healthText messaging

Identifiers

PMID26525857
PMCPMC4819010

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.