ArticleIranian endodontic journal2015
Cytotoxicity of a New Nano Zinc-Oxide Eugenol Sealer on Murine Fibroblasts.
Article in Iranian endodontic journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Retrieval of AH Plus, MTA Fillapex, and Endoseal MTA in Endodontic Retreatment: An in Vitro Cone-Beam Computed Tomography Study.Frontiers in dentistry · 2025Article
- A narrative review on application of metal and metal oxide nanoparticles in endodontics.Heliyon · 2024Review
- Niosomal Doxycycline and Triamcinolone: A Novel Approach to Minimize Cytotoxicity in Endodontic Medicaments.Iranian endodontic journal · 2024Article
- Application of Nanomaterials in Endodontics.BME frontiers · 2024Review
- Synthesis, characterization, and antiparasitic effects of zinc oxide nanoparticles-eugenol nanosuspension againstHeliyon · 2023Article
- Hematological and Biochemical Responses of Newly Formulated Primary Root Canal Obturating Material: An In Vivo Study.Cureus · 2022Article
- Nanomaterials Application in Endodontics.Materials (Basel, Switzerland) · 2021Review
- The Potential Translational Applications of Nanoparticles in Endodontics.International journal of nanomedicine · 2021Review
- Post-treatment Flare-up Incidence after Using Nano Zinc Oxide Eugenol Sealer in Mandibular First Molars with Irreversible Pulpitis.Journal of dentistry (Shiraz, Iran) · 2020Article
- Effect of incorporation of triphala into AH26 sealer on its cytotoxicity at different intervals.Journal of dental research, dental clinics, dental prospects · 2020Article
- Influence of Adding Nanoparticles of Silver Vanadate on Antibacterial Effect and Physicochemical Properties of Endodontic Sealers.Iranian endodontic journal · 2019Article
- Cytotoxicity of Selected Nanoparticles on Human Dental Pulp Stem Cells.Iranian endodontic journal · 2017Article
- Tooth Discoloration Resulting from a Nano Zinc Oxide-Eugenol Sealer.Iranian endodontic journal · 2017Article
- Subcutaneous Connective Tissue Reaction to a New Nano Zinc-Oxide Eugenol Sealer in Rat Model.Iranian endodontic journal · 2017Article
- Subcutaneous Reaction of Rat Tissues to Nanosilver Coated Gutta-Percha.Iranian endodontic journal · 2017Article
- Article
- Article
- Antibacterial Activity of MTA Fillapex and AH 26 Root Canal Sealers at Different Time Intervals.Iranian endodontic journal · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this study was to evaluate the cytotoxicity of a new nano zinc-oxide eugenol (NZOE) sealer in comparison with AH-26 and Pulpdent root canal sealers. METHODS AND MATERIALS: The L929 mouse fibroblast cells were cultivated and incubated for 24, 48 or 72 h with different dilutions (1/1, 1/2, 1/4, 1/8, 1/16 and 1/32) of culture media previously exposed to either of the test sealers naming NZOE, AH-26 or Pulpdent. At the end of incubation period, the effect of sealers on cell viability was evaluated using Mosmann's Tetrazolium Toxicity (MTT) colorimetric assay. The data was compared using the one-way analysis of variance (ANOVA) followed by the Tukey's post hoc test for multiple comparisons.
resultsAfter 24, 48 or 72 h, both NZOE and Pulpdent sealers inhibited cell viability at 1/1, 1/2 and 1/8 dilutions. Within the 24 and 48 h, the AH-26 sealer reduced the cell viability at all dilutions except the 1/32 solution; however after 72 h even the 1/32 dilution was cytotoxic.
conclusionThe biocompatibility of the nano zinc-oxide eugenol sealer was comparable to Pulpdent sealer and lower than AH-26.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.