ArticleInternational journal of immunopathology and pharmacology2016
Visfatin: New marker of oxidative stress in preterm newborns.
Article in International journal of immunopathology and pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Impact of Gestational Diabetes Mellitus on Fetal Growth and Nutritional Status in Newborns.Nutrients · 2024Review
- Targeted LC-MS/MS profiling of bile acids reveals primary/secondary bile acid ratio as a novel biomarker for necrotizing enterocolitis.Analytical and bioanalytical chemistry · 2024Article
- Visfatin aggravates transverse aortic constriction-induced cardiac remodelling by enhancing macrophage-mediated oxidative stress in mice.Journal of cellular and molecular medicine · 2023Article
- Role of visfatin in obesity-induced insulin resistance.World journal of clinical cases · 2022Review
- Evaluation of Genetic Polymorphisms of the Antioxidant Enzymes and Biomarkers of Oxidative Stress in Preterm Neonates With Respiratory Distress Syndrome Receiving External Surfactant.Biomarker insights · 2022Article
- Characteristics of Surgical Necrotizing Enterocolitis: Is It Different from Medical Necrotizing Enterocolitis? A Single-Center Retrospective Study.Children (Basel, Switzerland) · 2021Article
- Oxidative Stress in Preterm Newborns.Antioxidants (Basel, Switzerland) · 2021Review
- Association Between Platelet-to-Lymphocyte Ratio and Preterm Necrotizing Enterocolitis.Frontiers in pediatrics · 2021Article
- Review
- A modified physiologic test for bronchopulmonary dysplasia: a clinical tool for weaning from CPAP and/or oxygen-therapy the premature babies?Italian journal of pediatrics · 2019Article
- Current status of laboratory and imaging diagnosis of neonatal necrotizing enterocolitis.Italian journal of pediatrics · 2018Review
- Oxidative Stress as a Primary Risk Factor for Brain Damage in Preterm Newborns.Frontiers in pediatrics · 2018Review
- Oxidative Stress Related Diseases in Newborns.Oxidative medicine and cellular longevity · 2016Review
- Cord Blood Adiponectin and Visfatin Concentrations in relation to Oxidative Stress Markers in Neonates Exposed and Nonexposed In Utero to Tobacco Smoke.Oxidative medicine and cellular longevity · 2016Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOxidative stress is involved in several neonatal conditions characterized by an upregulation in the production of oxidative or nitrative free radicals and a concomitant decrease in the availability of antioxidant species. Oxygen, which is obviously vital to survival, can be highly damaging to neonatal tissue which is known to be poorly equipped to neutralize toxic derivatives. Thus, exposure of the newborn infant to high oxygen concentrations during resuscitation at birth increases oxidative damage. Visfatin is an adipocytokine involved in oxidative stress and an important mediator of inflammation that induces dose-dependent production of both pro-inflammatory and anti-inflammatory cytokines. To our knowledge, the diagnostic value of visfatin as a marker of oxidative stress in preterm newborns has not been investigated.
objectiveThe aim of this study was to evaluate visfatin levels in preterm neonates resuscitated with different concentrations of oxygen in the delivery room. PATIENTS: Fifty-two preterm newborns with gestational age less than 32 weeks, resuscitated randomly with different oxygen concentrations (40%, 60%, or 100%) were enrolled at the University Hospital of Messina, over a 12-month period to evaluate serum visfatin levels at T0 (within 1 h after birth), T24 h, T72 h, and T168 h of life.
resultsAt T72 h and T168 h, higher serum visfatin values in the high-oxygen group compared to the low- and mild-oxygen subjects (P=0.002 and P<0.001, respectively) were noted.
conclusionThe results of this study suggest that visfatin could be a new marker of oxidative stress in preterm newborns.
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