Evidence map›Paper›PMID 26525221›Full record

ArticleAIDS and behavior2016

Improvements in Depression and Changes in Fatigue: Results from the SLAM DUNC Depression Treatment Trial.

Julie Barroso, Angela M Bengtson, Bradley N Gaynes, Teena McGuinness, Evelyn B Quinlivan, Michelle Ogle, Amy Heine, Nathan M Thielman, Brian W Pence

Abstract read
In one paragraph

Article in AIDS and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. A Critical Review of Symptom Management Nursing Science on HIV-Related Fatigue and Sleep Disturbance.International journal of environmental research and public health · 2021
    Review
  3. Article
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Julie BarrosoCollege of Nursing, Medical University of South Carolina, Charleston, SC, USA. julievbarroso@gmail.com.
Angela M BengtsonDepartment of Epidemiology, University of North Carolina-Chapel Hill, Chapel Hill, USA.
Bradley N GaynesDepartment of Psychiatry, University of North Carolina-Chapel Hill, Chapel Hill, USA.
Teena McGuinnessSchool of Nursing, University of Alabama-Birmingham, Birmingham, USA.
Evelyn B QuinlivanDivision of Infectious Diseases, University of North Carolina-Chapel Hill, Chapel Hill, USA.
Michelle OgleWarren-Vance Community Health Center, Henderson, NC, USA.
Amy HeineDivision of Infectious Diseases, University of North Carolina-Chapel Hill, Chapel Hill, USA.
Nathan M ThielmanDivision of Infectious Diseases, Duke University, Durham, USA.
Brian W PenceDepartment of Epidemiology, University of North Carolina-Chapel Hill, Chapel Hill, USA.
University of North Carolina at Chapel Hill · USCommunity Health Center · USDuke University · USMedical University of South Carolina · USUniversity of Alabama at Birmingham · US

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Training in Sexually Transmitted Infections and HIVT32AI007001 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SENA-SOBERANO, ARLENE C. · 1985 to 2025
$10.9M
Improving HAART Adherence in Depressed HIV Clinic Patients: A Real-World RCTR01MH086362 · NIMH · DUKE UNIVERSITY · PI PENCE, BRIAN W · 2009 to 2013
$3.5M
NIAID NIH HHS P30 AI027767NIAID NIH HHS P30-AI027767NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI064518NIAID NIH HHS P30-AI064518NIAID NIH HHS P30-AI50410NIAID NIH HHS T32 AI007001NIAID NIH HHS T32-AI007001NIMH NIH HHS R01 MH086362NIMH NIH HHS R01-MH086362
6 · The paper itself

Abstract

Fatigue and depression are common co-morbid conditions among people with HIV infection. We analyzed a population of HIV-infected adults with depression, who were enrolled in a depression treatment trial, to examine the extent to which improvements in depression over time were associated with improvements in HIV-related fatigue. Data for this analysis come from a randomized controlled trial to evaluate the effectiveness of improved depression treatment on antiretroviral adherence. Fatigue was measured using the HIV-Related Fatigue Scale, and depressive symptoms were measured with the Hamilton Depression Rating Scale. Participants (n = 234) were on average nearly 44 years of age and predominantly male, black or African American, and unemployed. Individuals who experienced stronger depression response (i.e., greater improvement in depression score) had larger decreases in fatigue. However, even among those who demonstrated a full depression response, nearly three-quarters continued to have either moderate or severe fatigue at 6 and 12 months.

Indexed as

AdultAntidepressive AgentsAnti-Retroviral AgentsDepressionDose-Response Relationship, DrugFatigueFemaleHIV InfectionsHumansLongitudinal StudiesMajor Depressive DisorderMaleMiddle AgedMultivariate AnalysisNeuropsychological TestsPsychiatric Status Rating ScalesAntidepressive AgentsAnti-Retroviral AgentsDepressionFatigueInterventionSyndemic

Identifiers

PMID26525221
PMCPMC4905567
OpenAlexW2095876629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.