ArticlePediatric nephrology (Berlin, Germany)2016
Differences between the pediatric and adult presentation of fibromuscular dysplasia: results from the US Registry.
Article in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 90 citations in OpenAlex.
- Prevalence of aortic findings among patients with multifocal fibromuscular dysplasia (FMD) seen at a specialised referral centre.Open heart · 2026Article
- Pediatric fibromuscular dysplasia presenting with acute right lower extremity limb ischemia requiring endovascular treatment and amputation - a case report.BMC pediatrics · 2026Article
- Fibromuscular Dysplasia and Cerebrovascular Dissection: Insights From a Multicenter Cohort.Journal of the American Heart Association · 2026Article
- Aorto-Renal Dysplasia in Childhood: The Overlap of Neurofibromatosis Type 1 and Pediatric Renovascular Hypertension.Current hypertension reports · 2026Review
- Cerebrovascular fibromuscular dysplasia.Therapeutic advances in neurological disorders · 2026Review
- Complex equilibrium involving aldosterone underlies the pathophysiology of renovascular hypertension.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2025Article
- Renal Artery Stenosis and Mid-Aortic Syndrome in Children-A Review.Journal of clinical medicine · 2024Review
- Cerebral arteriopathies of childhood and stroke - A focus on systemic arteriopathies and pediatric fibromuscular dysplasia (FMD).Vascular medicine (London, England) · 2024Review
- Cerebral Infarction and Recovery in a 12-Year-Old Child With Intracranial Fibromuscular Dysplasia.Brain & NeuroRehabilitation · 2023Article
- Intravascular ultrasound provides additional insights in the hypertensive patients with focal renal artery fibromuscular dysplasia.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Observational
- Percutaneous Transluminal Renal Angioplasty for Fibromuscular Dysplasia and Prognostic Risk Factors: A Retrospective Chinese Cohort Study.Journal of clinical medicine · 2022Article
- Renovascular hypertension in pediatric patients: update on diagnosis and management.Pediatric nephrology (Berlin, Germany) · 2021Review
- Clinical characteristics and long-term outcomes of endovascular treatment of renal artery fibromuscular dysplasia with branch lesions.Pediatric nephrology (Berlin, Germany) · 2021Article
- Timing of procedural interventions in childhood renovascular hypertension.Pediatric nephrology (Berlin, Germany) · 2021Article
- FMD and SCAD: Sex-Biased Arterial Diseases With Clinical and Genetic Pleiotropy.Circulation research · 2021Article
- Fibromuscular dysplasia with unilateral renal agenesis.BMJ case reports · 2021Article
- Renovascular hypertension in children.CVIR endovascular · 2021Review
- Efficacy of Antihypertensive Therapy in a Child with Unilateral Focal Fibromuscular Dysplasia of the Renal Artery: A Case Study and Review of Literature.Medicines (Basel, Switzerland) · 2020Article
- Clinical course and prognostic factors of childhood Takayasu's arteritis: over 15-year comprehensive analysis of 101 patients.Arthritis research & therapy · 2019Observational
- Imaging studies in pediatric fibromuscular dysplasia (FMD): a single-center experience.Pediatric nephrology (Berlin, Germany) · 2018Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFibromuscular dysplasia (FMD) is a non-inflammatory arteriopathy that causes significant morbidity in children.
methodsThe clinical features, presenting symptoms, and vascular beds involved are reviewed in the first 33 patients aged <18 years who are enrolled in the United States Registry for FMD from five registry sites and compared with 999 adult patients from 12 registry sites.
resultsMean age at diagnosis was 8.4 ± 4.8 years (16 days to 17 years). Compared with adults, pediatric FMD occurs in more males (42.4 vs 6 %, p < 0.001). Children with FMD have a stronger previous history of hypertension (93.9 vs 69.9 %, p = 0.002). Hypertension (100 %), headache (55 %), and abdominal bruits (10.7 %) were the most common presenting signs and symptoms. FMD affects renal vasculature in almost all children (97 vs 69.7 %, p = 0.003). The extra-cranial carotid vessels are less commonly involved in children (23.1 vs 73.3 %, p < 0.001). The mesenteric arteries (38.9 vs 16.2 %, p = 0.02) and aorta (26.3 vs 2.4 %, p < 0.001) are more commonly involved in children.
conclusionsIn the United States Registry for FMD, pediatric FMD affects children from infancy throughout childhood. All children presented with hypertension and many presented with headache and abdominal bruits. In children, FMD most commonly affects the renal vasculature, but also frequently involves the mesenteric arteries and abdominal aorta; the carotid vessels are less frequently involved.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.