Evidence map›Paper›PMID 26525087›Full record

Observational studyThe journals of gerontology. Series A, Biological sciences and medical sciences2016

Motor Function Is Associated With Incident Disability in Older African Americans.

Aron S Buchman, Robert S Wilson, Lei Yu, Patricia A Boyle, David A Bennett, Lisa L Barnes

Abstract readObservational Study
In one paragraph

Observational study in The journals of gerontology. Series A, Biological sciences and medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Mobility Abilities Mediate the Association of a More Active Lifestyle With Mobility Disability in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Cognitive Training Attenuates Decline in Physical Function Across 10 Years.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Body Composition Remodeling and Incident Mobility Limitations in African Ancestry Men.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aron S BuchmanRush Alzheimer's Disease Center, Department of Neurological Sciences, and Aron_S_Buchman@rush.edu.
Robert S WilsonRush Alzheimer's Disease Center, Department of Neurological Sciences, and Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois.
Lei YuRush Alzheimer's Disease Center, Department of Neurological Sciences, and.
Patricia A BoyleRush Alzheimer's Disease Center, Department of Neurological Sciences, and Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois.
David A BennettRush Alzheimer's Disease Center, Department of Neurological Sciences, and.
Lisa L BarnesRush Alzheimer's Disease Center, Department of Neurological Sciences, and Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois.

Funding

SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1991 to 2020
$49.1M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
The Clinical Profile of Parkinson's Disease (PD) PathologyR01NS078009 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI BUCHMAN, ARON S · 2012 to 2016
$2.4M
NIA NIH HHS P30 AG010161NIA NIH HHS P30AG10161NIA NIH HHS R01 AG022018NIA NIH HHS R01AG22018NINDS NIH HHS R01 NS078009NINDS NIH HHS R01NS78009
6 · The paper itself

Abstract

backgroundDisability in older African American adults is common, but its basis is unclear. We tested the hypothesis that the level of motor function is associated with incident disability in older African Americans after adjusting for cognition.

methodsA prospective observational cohort study of 605 older community-dwelling African American adults without dementia was carried out. Baseline global motor score summarized 11 motor performances, cognition was based on 19 cognitive tests, and self-reported disability was obtained annually. We examined the association of motor function with incident disability (instrumental activities of daily living [IADL], activities of daily living [ADL], and mobility disability) with a series of Cox proportional hazards models which controlled for age, sex, and education.

resultsAverage follow-up was about 5 years. In proportional hazards models, a 1-SD increase in baseline level of global motor score was associated with about a 50% decrease in the risk of subsequent IADL, ADL, and mobility disability (all p values < .001). These associations were unchanged in analyses controlling for cognition and other covariates. Further, the association of global motor score and incident ADL disability varied with the level of cognition (estimate -5.541, SE 1.634, p < .001), such that higher motor function was more protective at higher levels of cognition. Mobility and dexterity components of global motor score were more strongly associated with incident disability than strength (all p values < .001).

conclusionsBetter motor function in older African Americans is associated with a decreased risk of developing disability. Moreover, the association of motor function and disability is stronger in individuals with better cognitive function.

Indexed as

Black or African AmericanMobility LimitationAgedAged, 80 and overCognitionCohort StudiesDisability EvaluationFemaleGeriatric AssessmentHumansMaleMotor ActivityProportional Hazards ModelsResidence CharacteristicsSelf ReportAfrican AmericansAgingCognitionDisabilityMotor function

Identifiers

PMID26525087
PMCPMC5007739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.