Evidence map›Paper›PMID 26525068›Full record

ReviewThe American journal of case reports2015

Non-Small Cell Lung Cancer in a Very Young Woman: A Case Report and Critical Review of the Literature.

Valentina Polo, Giulia Zago, Stefano Frega, Fabio Canova, Laura Bonanno, Adolfo Favaretto, Laura Bonaldi, Roberta Bertorelle, PierFranco Conte, Giulia Pasello

Open access · greenAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The American journal of case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Ground glass opacity featured lung adenocarcinoma in teenagers.Journal of cancer research and clinical oncology · 2021
    Article
  3. [Genetic Profile of Young Chinese Patients with Lung Adenocarcinoma].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020
    Article
  4. Article
  5. Expression of Molecular Markers in Primary Sites and Metastatic Lymph Nodes of Lung Cancer Patients.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Valentina PoloDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Giulia ZagoDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Stefano FregaDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Fabio CanovaDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Laura BonannoDivision of Medical Oncology 2, Istituto Oncologico Veneto IRCCS, Padova, Italy.
Adolfo FavarettoDivision of Medical Oncology 2, Istituto Oncologico Veneto IRCCS, Padova, Italy.
Laura BonaldiImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IRCCS, Padova, Italy.
Roberta BertorelleImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IRCCS, Padova, Italy.
PierFranco ConteDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Giulia PaselloDivision of Medical Oncology 2, Istituto Oncologico Veneto IRCCS, Padova, Italy.
University of Padua · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Oncologico Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung cancer in young patients is quite uncommon; clinical presentation and outcome in this population compared to the older group are not yet well defined and data about this setting are mostly single-institutional retrospective analyses. CASE REPORT: We report here a case of a very young woman with diagnosis of early-stage lung adenocarcinoma harboring EML4-ALK rearrangement; she underwent radical surgery and adjuvant chemotherapy according to the pathologic stage. Potential risk factors for lung cancer in our patient are discussed and clinico-pathologic features and outcomes of lung cancer in the young population compared to the elderly are reviewed through discussing studies with sample sizes larger than 100 patients.

conclusionsA wide clinical overview should be performed when lung cancer is diagnosed in a young patient. Large-population studies are required to define the molecular signature and clinical behavior of lung cancer in young patients.

Indexed as

Carcinoma, Non-Small-Cell LungDNA, NeoplasmFemaleGene RearrangementGenetic TestingHumansLung NeoplasmsOncogene Proteins, FusionPneumonectomyThoracic Surgery, Video-AssistedTomography, X-Ray ComputedYoung AdultDNA, NeoplasmEML4-ALK fusion protein, humanOncogene Proteins, Fusion

Identifiers

PMID26525068
PMCPMC4642365
OpenAlexW1916249863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.