Evidence map›Paper›PMID 26524964›Full record

ArticleJournal of immunology research2015

Adaptation to Resistance Training Is Associated with Higher Phagocytic (but Not Oxidative) Activity in Neutrophils of Older Women.

João Bartholomeu-Neto, Ciro José Brito, Otávio Toledo Nóbrega, Vinícius Carolino Sousa, Juliana Oliveira Toledo, Roberta Silva Paula, David Junger Fonseca Alves, Aparecido Pimentel Ferreira, Clayton Franco Moraes, Cláudio Córdova

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

João Bartholomeu-NetoCatholic University of Brasília, 71966-700 Brasília, DF, Brazil.
Ciro José BritoFederal University of Juiz de Fora, 36036-330 Governador Valadares, MG, Brazil.
Otávio Toledo NóbregaUniversity of Brasília, 70910-900 Brasília, DF, Brazil.
Vinícius Carolino SousaUniversity of Brasília, 70910-900 Brasília, DF, Brazil.
Juliana Oliveira ToledoUniversity of Brasília, 70910-900 Brasília, DF, Brazil.
Roberta Silva PaulaUniversity of Brasília, 70910-900 Brasília, DF, Brazil.
David Junger Fonseca AlvesCatholic University of Brasília, 71966-700 Brasília, DF, Brazil.
Aparecido Pimentel FerreiraPaulista University, 70390-130 Brasília, DF, Brazil.
Clayton Franco MoraesCatholic University of Brasília, 71966-700 Brasília, DF, Brazil ; University of Brasília, 70910-900 Brasília, DF, Brazil.
Cláudio CórdovaCatholic University of Brasília, 71966-700 Brasília, DF, Brazil.
Universidade Católica de Brasília · BRUniversidade de Brasília · BRUniversidade Federal de Juiz de Fora · BRUniversidade Paulista · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Failure in antimicrobial activity contributes to high morbidity and mortality in the geriatric population. Little is known about the potential effect of resistance training (RT) on the functional properties of the innate immunity. This study aimed to investigate the influence of long-term RT on the endocytic and oxidative activities of neutrophils and monocytes in healthy older women. Our results indicate that the phagocytosis index (PhI) of neutrophils (but not of monocytes) in the RT-adapted group was significantly higher (P < 0.001; effect size, (d) = 0.90, 95% CI: [0.75-1.04]) compared to that in sedentary subjects. In contrast, the oxidative activity of either neutrophils or monocytes was not significantly influenced by RT. Also, total energy and carbohydrate intake as well as serum IL6 levels had a significant influence on the phagocytic activity of neutrophils (P = 0.04), being considered in the model. Multivariate regression identified the physical condition of the subject (β = 0.425; P = 0.01) as a significant predictor of PhI. In conclusion, circulating neutrophils of older women adapted to a long-term RT program expressed higher phagocytic activity.

Indexed as

Adaptation, PhysiologicalResistance TrainingAgedAge FactorsBiomarkersCytokinesFemaleHumansImmunity, InnateLeukocyte CountNeutrophilsOxidation-ReductionPhagocytosisRisk FactorsSex FactorsBiomarkersCytokines

Identifiers

PMID26524964
PMCPMC4617425
OpenAlexW1896617592

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.