Evidence map›Paper›PMID 26524301›Full record

ArticleJournal of synchrotron radiation2015

A modular and compact portable mini-endstation for high-precision, high-speed fixed target serial crystallography at FEL and synchrotron sources.

Darren A Sherrell, Andrew J Foster, Lee Hudson, Brian Nutter, James O'Hea, Silke Nelson, Olivier Paré-Labrosse, Saeed Oghbaey, R J Dwayne Miller, Robin L Owen

Abstract read
In one paragraph

Article in Journal of synchrotron radiation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Microfluidic Devices for High-Throughput In Situ Serial Crystallography.Advances in biochemical engineering/biotechnology · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Anaerobic fixed-target serial crystallography using sandwiched silicon nitride membranes.Acta crystallographica. Section D, Structural biology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Best practices for time-resolved serial synchrotron crystallography.Acta crystallographica. Section D, Structural biology · 2022
    Review
  20. Versatile microporous polymer-based supports for serial macromolecular crystallography.Acta crystallographica. Section D, Structural biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Darren A SherrellDiamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 ODE, UK.
Andrew J FosterDiamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 ODE, UK.
Lee HudsonDiamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 ODE, UK.
Brian NutterDiamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 ODE, UK.
James O'HeaDiamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 ODE, UK.
Silke NelsonLCLS, SLAC National Laboratory, Menlo Park, CA 94025, USA.
Olivier Paré-LabrosseDepartment of Chemistry and Physics, University of Toronto, 80 St George St, Toronto, ON M5S 1A8, Canada.
Saeed OghbaeyDepartment of Chemistry and Physics, University of Toronto, 80 St George St, Toronto, ON M5S 1A8, Canada.
R J Dwayne MillerDepartment of Chemistry and Physics, University of Toronto, 80 St George St, Toronto, ON M5S 1A8, Canada.
Robin L OwenDiamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 ODE, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The design and implementation of a compact and portable sample alignment system suitable for use at both synchrotron and free-electron laser (FEL) sources and its performance are described. The system provides the ability to quickly and reliably deliver large numbers of samples using the minimum amount of sample possible, through positioning of fixed target arrays into the X-ray beam. The combination of high-precision stages, high-quality sample viewing, a fast controller and a software layer overcome many of the challenges associated with sample alignment. A straightforward interface that minimizes setup and sample changeover time as well as simplifying communication with the stages during the experiment is also described, together with an intuitive naming convention for defining, tracking and locating sample positions. The setup allows the precise delivery of samples in predefined locations to a specific position in space and time, reliably and simply.

Indexed as

fixed-target serial femtosecond crystallographymotion controlportable endstationsample delivery

Identifiers

PMID26524301
PMCPMC4629865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.