ArticleHuman brain mapping2016
DBSproc: An open source process for DBS electrode localization and tractographic analysis.
Article in Human brain mapping, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Measuring Subthalamic Nucleus Volume of Parkinson's Patients and Evaluating Its Relationship with Clinical Scales at Pre- and Postdeep Brain Stimulation Treatment: A Magnetic Resonance Imaging Study.BioMed research international · 2021Trial
- Mechanism and progress of deep brain stimulation in the treatment of neurological and psychiatric disorders.MedScience · 2026Review
- State-of-the-Art Imaging and Localization Assessment in Post-Operative Deep Brain Stimulation for Parkinson's Disease: A Review.Stereotactic and functional neurosurgery · 2026Review
- Article
- Lead-DBS v3.0: Mapping deep brain stimulation effects to local anatomy and global networks.NeuroImage · 2023Article
- Deciphering the Network Effects of Deep Brain Stimulation in Parkinson's Disease.Neurology and therapy · 2022Article
- Article
- Subthalamic-Cortical Network Reorganization during Parkinson's Tremor.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Dataset of concurrent EEG, ECG, and behavior with multiple doses of transcranial electrical stimulation.Scientific data · 2021Article
- Technology of deep brain stimulation: current status and future directions.Nature reviews. Neurology · 2021Review
- Executive function network's white matter alterations relate to Parkinson's disease motor phenotype.Neuroscience letters · 2021Article
- Linking immune-mediated damage to neurodegeneration in multiple sclerosis: could network-based MRI help?Brain communications · 2021Article
- Rapid motor fluctuations reveal short-timescale neurophysiological biomarkers of Parkinson's disease.Journal of neural engineering · 2020Article
- [Application of intracranial lead reconstruction in deep brain stimulation therapy in patients with Parkinson's disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019Article
- A Driving-Force Predictor for Estimating Pathway Activation in Patient-Specific Models of Deep Brain Stimulation.Neuromodulation : journal of the International Neuromodulation Society · 2019Article
- Deep Brain Stimulation Programming 2.0: Future Perspectives for Target Identification and Adaptive Closed Loop Stimulation.Frontiers in neurology · 2019Review
- Article
- ESM-CT: a precise method for localization of DBS electrodes in CT images.Journal of neuroscience methods · 2018Article
- Integrated analysis of anatomical and electrophysiological human intracranial data.Nature protocols · 2018Article
- Quantifying axonal responses in patient-specific models of subthalamic deep brain stimulation.NeuroImage · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Deep brain stimulation (DBS) is an effective surgical treatment for movement disorders. Although stimulation sites for movement disorders such as Parkinson's disease are established, the therapeutic mechanisms of DBS remain controversial. Recent research suggests that specific white-matter tract and circuit activation mediates symptom relief. To investigate these questions, we have developed a patient-specific open-source software pipeline called 'DBSproc' for (1) localizing DBS electrodes and contacts from postoperative CT images, (2) processing structural and diffusion MRI data, (3) registering all images to a common space, (4) estimating DBS activation volume from patient-specific voltage and impedance, and (5) understanding the DBS contact-brain connectivity through probabilistic tractography. In this paper, we explain our methodology and provide validation with anatomical and tractographic data. This method can be used to help investigate mechanisms of action of DBS, inform surgical and clinical assessments, and define new therapeutic targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.