Evidence map›Paper›PMID 26523252›Full record

ArticleJournal of cerebrovascular and endovascular neurosurgery2015

Endovascular Treatment for Acute Ischemic Stroke Patients over 80 Years of Age.

Kihwan Hwang, Gyojun Hwang, O-Ki Kwon, Chang Hyeun Kim, Seung Pil Ban, Moon-Ku Han, Hee-Joon Bae, Beom Joon Kim, Jae Seung Bang, Chang Wan Oh and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of cerebrovascular and endovascular neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Endovascular Stroke Treatment of Nonagenarians.AJNR. American journal of neuroradiology · 2017
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Kihwan HwangDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Gyojun HwangDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
O-Ki KwonDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Chang Hyeun KimDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Seung Pil BanDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Moon-Ku HanDepartment of Neurology, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Hee-Joon BaeDepartment of Neurology, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Beom Joon KimDepartment of Neurology, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Jae Seung BangDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Chang Wan OhDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Boram LeeDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Eun-A JeongDepartment of Neurosurgery, Regional Caridocerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Seoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe evaluated the effect of endovascular treatment (EVT) for acute ischemic stroke in patients over 80 years of age. MATERIALS AND

methodsThe records of 156 acute stroke patients aged over 80 years who were considered as candidates for EVT were analyzed. Fifty-six patients (35.9%, EVT group) underwent EVT and 100 patients (64.1%, non-EVT group) did not. Outcomes, in terms of functional outcomes and rates of symptomatic hemorrhage, in-hospital morbidity and mortality, were compared between groups. Each comparison was adjusted for age, time from onset, initial National Institute of Health Stroke Scale, and pre-stroke modified Rankin Scale (mRS).

resultsMore patients in the EVT group achieved good outcomes (mRS score of 0-2) at 3 months (35.7% vs. 11.0%, adjusted odds ratio [OR] 4.779 [95% confidence interval 1.972-11.579], p = 0.001) and 12 months (35.7% vs. 14.0%, adjusted OR 3.705 [1.574-8.722], p = 0.003) after stroke. During admission, rates of hospital-acquired infection including pneumonia (12.5% vs. 29.0%, adjusted OR 0.262 [0.098-0.703], p = 0.008) and urinary tract infection (16.0% vs. 34.0%, adjusted OR 0.256 [0.099-0.657], p = 0.005) were significantly lower in the EVT group. More symptomatic hemorrhages (10.7% vs. 2.0%, adjusted OR 6.859 [1.139-41.317], p = 0.036) occurred in the EVT group, but no significant difference was observed in in-hospital mortality rate (12.5% vs. 8.0%, adjusted OR 1.380 [0.408-4.664], p = 0.604).

conclusionEVT improved functional outcome and reduced the risk of hospital-acquired infections in acute stroke patients over 80 years of age without increasing the risk of in-hospital mortality, although symptomatic hemorrhage occurred more frequently after EVT.

Indexed as

AgedStrokeThrombolytic therapy

Identifiers

PMID26523252
PMCPMC4626339
OpenAlexW2285736152

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.