Evidence map›Paper›PMID 26523243›Full record

ArticleJournal of obesity & weight loss therapy2015

Exercise Training and Insulin Resistance: A Current Review.

Tyler E Keshel, Robert H Coker

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of obesity & weight loss therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04075799 (A HIIT to Improve Metabolic Health in Obese Adults With Insulin Resistance), which is not on this map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04075799 naterminatednot on this mapstarted 2022, after this paper: background citation

A HIIT to Improve Metabolic Health in Obese Adults With Insulin Resistance

TypeinterventionalSponsorUniversity of New MexicoRan2022 to 2023Enrolled18ConditionsObesity, Insulin ResistanceArmshigh-intensity interval training
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 76 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Exercise and Reduced Nicotine Content Cigarettes in Adult Female Smokers: A Pilot Trial.International journal of environmental research and public health · 2022
    Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Positive Effects of Physical Activity on Insulin Signaling.Current issues in molecular biology · 2024
    Review
  13. Physical activity in metabolic syndrome.Frontiers in physiology · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tyler E KeshelInstitute of Arctic Biology, University of Alaska-Fairbanks, Fairbanks, AK, USA.
Robert H CokerInstitute of Arctic Biology, University of Alaska-Fairbanks, Fairbanks, AK, USA ; Center for Translational Research in Aging and Longevity, Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
University of Alaska Fairbanks · US

Funding

Pilot Project ProgramP30GM103325 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI COKER, ROBERT H. · 2012 to 2016
$5.3M
Therapeutic Adaptation of Insulin Action in HumansK01DK064716 · NIDDK · UNIV OF ARKANSAS FOR MED SCIS · PI COKER, ROBERT H · 2004 to 2007
$536k
NIDDK NIH HHS K01 DK064716NIGMS NIH HHS P30 GM103325
6 · The paper itself

Abstract

There is a general perception that increased physical activity will improve glucose homeostasis in all individuals. While this is an attractive concept, this conclusion may be overly simplistic and even misleading. The topic was reviewed extensively over 30 years ago and it was concluded that acute exercise enhances glucose uptake. However, in some cases the chronic influence of interventions utilizing exercise may have little effect on glucose metabolism. Moreover, insulin resistance often returns to near baseline levels within a couple of days following cessation of the exercise bout; leaving the overall effectiveness of the intervention in question. Since improving glucose homeostasis should be the focal endpoint of any intervention designed to mitigate the overwhelming degree of insulin resistance in individuals at risk for metabolic disease, it is essential to evaluate the key components of a successful approach.

Indexed as

InflammationMetabolismWeight loss

Identifiers

PMID26523243
PMCPMC4625541
OpenAlexW2111405129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.