Evidence map›Paper›PMID 26523214›Full record

ArticleHealth2015

What Do We Know about Individuals Who Are Assessed as Being at Moderate Risk for Future Fracture in Canada?

Joanna E M Sale, Ravi Jain, Kosalan Akilan, Kevin Senior, Dorcas Beaton, Earl Bogoch, Gilles Boire, Marie-Claude Beaulieu, David Lightfoot, Larry Funnell

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00512499 (Osteoporosis and Peripheral Fractures), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00512499 nacompletednot on this map

Osteoporosis and Peripheral Fractures: Treatment and Investigation Multidisciplinary at the chUS

TypeinterventionalSponsorUniversité de SherbrookeRan2007 to 2016Enrolled1,410ConditionsOsteoporosis, FracturesArmsControl group, Minimal Intervention, Intensive Intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. A pragmatic proposal for triaging DXA testing during the COVID-19 global pandemic.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Joanna E M SaleMusculoskeletal Health and Outcomes Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada ; Institute of Health Policy, Management & Evaluation, University of Toronto, Toronto, Canada.
Ravi JainOsteoporosis Canada, Toronto, Canada.
Kosalan AkilanMusculoskeletal Health and Outcomes Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.
Kevin SeniorMusculoskeletal Health and Outcomes Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.
Dorcas BeatonMusculoskeletal Health and Outcomes Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada ; Institute of Health Policy, Management & Evaluation, University of Toronto, Toronto, Canada.
Earl BogochMobility Program, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada ; Department of Surgery, University of Toronto, Toronto, Canada.
Gilles BoireDepartment of Medicine, Division of Rheumatology, Université de Sherbrooke, Sherbrooke, Canada.
Marie-Claude BeaulieuDepartment of Family Medicine and Emergency Medicine, Université de Sherbrooke, Sherbrooke, Canada.
David LightfootMusculoskeletal Health and Outcomes Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.
Larry FunnellOsteoporosis Canada, Toronto, Canada.
St. Michael's Hospital · CAOsteoporosis Canada · CAUniversité de Sherbrooke · CA

Funding

CIHR 119522-1CIHR 136622-1PHS HHS 119522-1PHS HHS 136622-1
6 · The paper itself

Abstract

objectiveWe examined what was known about individuals in Canada who were assessed as being at moderate risk for future fracture.

methodsA scoping review was conducted. Eligible articles were Canadian studies published from 2010 onwards reporting on primary data that included patients at moderate risk for future fracture. We limited the search to Canada as fracture risk categorization is unique to each country. Studies were identified by searching relevant databases. Two reviewers independently reviewed titles and abstracts to determine each study's eligibility. General information about each study, demographic information about the moderate risk groups (including tool used to determine moderate risk (Fracture Risk Assessment Tool (FRAX), Canadian Association of Radiologists and Osteoporosis Canada (CAROC)), and outcomes (number of patients: recommended treatment, prescribed treatment, initiating treatment, persisting with treatment after six months, who re-fractured, who died) were documented.

resultsWe identified 1193 papers which were further screened for eligibility. Of the 1193 identified, 7 were eligible for the review but only 4 articles contained demographic or outcome data on moderate risk patients. In one study, 1.8% of moderate risk patients died over a mean 5.3 years of observation and in three studies, the risk of fracture was 5.9% over a median of 3 years of follow-up, 8.3% over a mean of 5.4 years, and 14.7% over 10 years of follow-up.

conclusionThere is a wide knowledge gap in the literature concerning individuals who are assessed as moderate risk for future fracture in Canada.

Indexed as

ManagementModerate RiskOsteoporosisOutcomesScoping Review

Identifiers

PMID26523214
PMCPMC4623758
OpenAlexW2103099680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.