ArticleInternational journal of clinical rheumatology
Raynaud's phenomenon and digital ischemia: a practical approach to risk stratification, diagnosis and management.
Article in International journal of clinical rheumatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Use of nitroglycerin ointment to treat primary and secondary Raynaud's phenomenon: a systematic literature review.Rheumatology international · 2018Pooled it
- The effects of upper and lower limb exercise on the microvascular reactivity in limited cutaneous systemic sclerosis patients.Arthritis research & therapy · 2018Trial
- Acute Finger Ischemia Evaluated With Point-Of-Care-Ultrasound and Diagnosed With Concurrent Polycythemia Vera, Antiphospholipid Syndrome, and Tobacco Use.Clinical case reports · 2026Article
- Palliative care in systemic sclerosis: incorporating advance care planning into longitudinal care.Journal of scleroderma and related disorders · 2026Review
- Case Report: HHS-spectrum distal palmar arterial thrombosis in a volleyball athlete with provocative-position thoracic outlet narrowing.Frontiers in cardiovascular medicine · 2026Article
- Macrovascular Involvement in Systemic Sclerosis: Association Between Carotid Ultrasound Hemodynamics Parameters and Digital Ulcers.Clinics and practice · 2025Article
- Unveiling the Enigma: Idiopathic Digital Infarction-A Case Report and Literature Review.Clinical case reports · 2025Article
- Prevalence and severity of complicated Raynaud's phenomenon in limited and diffuse systemic sclerosis: a multicenter study in Iraq.Reumatologia · 2025Article
- Article
- Anti-PL-12 anti-synthetase syndrome manifesting with multiple digital ischemia: Case report & review of the literature.Clinical case reports · 2024Article
- Distal periarterial sympathectomy surgery for chronic digital ischemia: A systematic review of the literature.Journal of orthopaedics · 2024Article
- Black Digits Matter: A Multispecialty Enigma.Cureus · 2024Article
- Gemcitabine-induced peripheral vascular disease and prolonged response in a patient with metastatic pancreatic adenocarcinoma: A case report.World journal of clinical cases · 2023Article
- Ultrasound Detection of Calcinosis and Association With Ulnar Artery Occlusion in Patients With Systemic Sclerosis.Arthritis care & research · 2021Article
- Vasopressor-Induced Digital Ischemia.Cureus · 2021Article
- Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases.Frontiers in oncology · 2021Article
- Innovations in the Assessment of Primary and Secondary Raynaud's Phenomenon.Frontiers in pharmacology · 2019Article
- Bilateral Brachial Artery Disease Presenting with Features of Raynaud's Phenomenon: A Case Report and Review of the Literature.Case reports in vascular medicine · 2017Article
- Difficulties in diagnosis and treatment of severe secondary Raynaud's phenomenon in a Cameroonian woman: a case report.Journal of medical case reports · 2016Article
- My approach to the treatment of scleroderma.Mayo Clinic proceedings · 2013Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Digital ischemia is a painful and often disfiguring event. Such an ischemic event often leads to tissue loss and can significantly affect the patient's quality of life. Digital ischemia can be secondary to a vasculopathy, vasculitis, embolic disease, trauma, or extrinsic vascular compression. It is an especially serious complication in patients with scleroderma. Risk stratification of patients with scleroderma at risk for digital ischemia is now possible with clinical assessment and autoantibody profiles. Because there are a variety of conditions that lead to digital ischemia, it is important to understand the pathophysiology underlying each ischemic presentation in order to target therapy appropriately. Significant progress has been made in the last two decades in defining the pathophysiological processes leading to digital ischemia in rheumatic diseases. In this article we review the risk stratification, diagnosis, and management of patients with digital ischemia and provide a practical approach to therapy, particularly in scleroderma.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.