Evidence map›Paper›PMID 26523109›Full record

ReviewWorld journal of gastroenterology2015

Dysbiotic infection in the stomach.

Hisashi Iizasa, Shyunji Ishihara, Timmy Richardo, Yuichi Kanehiro, Hironori Yoshiyama

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Roles of the gut microbiota in severe SARS-CoV-2 infection.Cytokine & growth factor reviews · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Fungi, host immune response, and tumorigenesis.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Review
  9. Article
  10. Article
  11. The Protective Effects of Helicobacter pylori Infection on Allergic Asthma.International archives of allergy and immunology · 2021
    Review
  12. Article
  13. Review
  14. Human Gut Microbiota and Gastrointestinal Cancer.Genomics, proteomics & bioinformatics · 2018
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hisashi IizasaHisashi Iizasa, Timmy Richardo, Yuichi Kanehiro, Hironori Yoshiyama, Department of Microbiology, Shimane University Faculty of Medicine, Shimane 693-8501, Japan.
Shyunji IshiharaHisashi Iizasa, Timmy Richardo, Yuichi Kanehiro, Hironori Yoshiyama, Department of Microbiology, Shimane University Faculty of Medicine, Shimane 693-8501, Japan.
Timmy RichardoHisashi Iizasa, Timmy Richardo, Yuichi Kanehiro, Hironori Yoshiyama, Department of Microbiology, Shimane University Faculty of Medicine, Shimane 693-8501, Japan.
Yuichi KanehiroHisashi Iizasa, Timmy Richardo, Yuichi Kanehiro, Hironori Yoshiyama, Department of Microbiology, Shimane University Faculty of Medicine, Shimane 693-8501, Japan.
Hironori YoshiyamaHisashi Iizasa, Timmy Richardo, Yuichi Kanehiro, Hironori Yoshiyama, Department of Microbiology, Shimane University Faculty of Medicine, Shimane 693-8501, Japan.
Shimane University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbiota in human alimentary tract plays important roles for homeostatic maintenance of the body. Compositional difference of gut microbiota is tightly associated with susceptibility of many diseases, including inflammatory diseases, obesity, diabetes mellitus, cancer, and atherosclerosis. "Dysbiosis" refers to a state of imbalance among the colonies of microorganisms within the body, which brings abnormal increase of specific minor components and decrease in the normally dominant species. Since stomach secrets strong acid for its digestive role, this organ has long been thought a sterile organ. However, the discovery of Helicobacter pylori (H. pylori) has changed the concept. This bacterium has proven to cause gastritis, peptic ulcer, and gastric cancer. However, recent cross-sectional studies revealed that H. pylori carriers had a decreased risk of developing immunological diseases, such as asthma. H. pylori coinfection also suppresses inflammatory bowel diseases. This review describes human gastric microbiota by discussing its mutual interaction and pathogenic enrollment. Gastric "dysbiosis" may affect host inflammatory response and play important role for gastric pathogenesis. We will topically discuss enrollment of dysbiosis for genesis of gastric cancer as well as for disruption of immunological homeostasis affecting oncogenic resistance.

Indexed as

DysbiosisGastrointestinal MicrobiomeGastric AcidGastric MucosaHelicobacter InfectionsHelicobacter pyloriHomeostasisHost-Pathogen InteractionsHumansRisk FactorsStomachStomach NeoplasmsDysbiosisEpstein-Barr virusHelicobacter pyloriMicrobiotaStomach

Identifiers

PMID26523109
PMCPMC4616220
OpenAlexW1897846045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.