Evidence map›Paper›PMID 26523103›Full record

ReviewWorld journal of gastroenterology2015

Irritable bowel syndrome and chronic constipation: Fact and fiction.

Massimo Bellini, Dario Gambaccini, Paolo Usai-Satta, Nicola De Bortoli, Lorenzo Bertani, Santino Marchi, Cristina Stasi

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. The laxative efficacy of a mixed extract ofOpen veterinary journal · 2026
    Article
  5. Article
  6. The Efficacy of Lubiprostone in Patients of Constipation: An Updated Systematic Review and Meta-Analysis.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Review
  7. Article
  8. Article
  9. Relationship between Depression and Constipation: Results from a Large Cross-sectional Study in Adults.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022
    Article
  10. Review
  11. Laxative Use in the Community: A Literature Review.Journal of clinical medicine · 2021
    Review
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Massimo BelliniMassimo Bellini, Dario Gambaccini, Nicola De Bortoli, Lorenzo Bertani, Santino Marchi, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, 56124 Pisa, Italy.
Dario GambacciniMassimo Bellini, Dario Gambaccini, Nicola De Bortoli, Lorenzo Bertani, Santino Marchi, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, 56124 Pisa, Italy.
Paolo Usai-SattaMassimo Bellini, Dario Gambaccini, Nicola De Bortoli, Lorenzo Bertani, Santino Marchi, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, 56124 Pisa, Italy.
Nicola De BortoliMassimo Bellini, Dario Gambaccini, Nicola De Bortoli, Lorenzo Bertani, Santino Marchi, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, 56124 Pisa, Italy.
Lorenzo BertaniMassimo Bellini, Dario Gambaccini, Nicola De Bortoli, Lorenzo Bertani, Santino Marchi, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, 56124 Pisa, Italy.
Santino MarchiMassimo Bellini, Dario Gambaccini, Nicola De Bortoli, Lorenzo Bertani, Santino Marchi, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, 56124 Pisa, Italy.
Cristina StasiMassimo Bellini, Dario Gambaccini, Nicola De Bortoli, Lorenzo Bertani, Santino Marchi, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, 56124 Pisa, Italy.
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) and functional constipation (FC) are the most common functional gastrointestinal disorders. According to the Rome III Criteria these two disorders should be theoretically separated mainly by the presence of abdominal pain or discomfort relieved by defecation (typical of IBS) and they should be mutually exclusive. However, many gastroenterologists have serious doubts as regards a clear separation. Both IBS-C and FC, often associated with many other functional digestive and non digestive disorders, are responsible for a low quality of life. The impact of the media on patients' perception of these topics is sometimes disruptive, often suggesting a distorted view of pathophysiology, diagnosis and therapy. These messages frequently overlap with previous subjective opinions and are further processed on the basis of the different culture and the previous experience of the constipated patients, often producing odd, useless or even dangerous behaviors. The aim of this review was to analyze the most common patients' beliefs about IBS-C and CC, helping physicians to understand where they should focus their attention when communicating with patients, detecting false opinions and misconceptions and correcting them on the basis of scientific evidence.

Indexed as

Abdominal PainChronic DiseaseConstipationDefecationGastrointestinal TransitHealth BehaviorHealth Knowledge, Attitudes, PracticeHumansIntestinesIrritable Bowel SyndromePatient Education as TopicPublic OpinionChronic constipationFunctional constipationIrritable bowel syndrome

Identifiers

PMID26523103
PMCPMC4616212
OpenAlexW2172628035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.