Evidence map›Paper›PMID 26523098›Full record

ReviewWorld journal of gastroenterology2015

Diagnosis of Helicobacter pylori infection: Current options and developments.

Yao-Kuang Wang, Fu-Chen Kuo, Chung-Jung Liu, Meng-Chieh Wu, Hsiang-Yao Shih, Sophie S W Wang, Jeng-Yih Wu, Chao-Hung Kuo, Yao-Kang Huang, Deng-Chyang Wu

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 200 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
200citing papers in PubMed, 7 pooled it
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

200 citing papers in PubMed, 7 syntheses or guidelines pooled it, 410 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. The Relationship betweenCanadian journal of gastroenterology & hepatology · 2021
    Pooled it
  5. Medicina (Kaunas, Lithuania) · 2019
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Article
  12. Article
  13. Helicobacter pylori eradication in the face of escalating anti-microbial resistance: Geographic heterogeneity and emerging treatment strategies.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  14. Accuracy and Agreement of a 45 mg Versus a 75 mgDiagnostics (Basel, Switzerland) · 2026
    Article
  15. Frequency ofCanadian liver journal · 2026
    Article
  16. Article
  17. Gastric neoplasm with foveolar-cell differentiation inHistology and histopathology · 2026
    Review
  18. Article
  19. Article
  20. Current concepts of Helicobacter pylori infection.European journal of medical research · 2025
    Review

140 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Yao-Kuang WangYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Fu-Chen KuoYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Chung-Jung LiuYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Meng-Chieh WuYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Hsiang-Yao ShihYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Sophie S W WangYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Jeng-Yih WuYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Chao-Hung KuoYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Yao-Kang HuangYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
Deng-Chyang WuYao-Kuang Wang, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan.
University Gastroenterology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate diagnosis of Helicobacter pylori (H. pylori) infection is a crucial part in the effective management of many gastroduodenal diseases. Several invasive and non-invasive diagnostic tests are available for the detection of H. pylori and each test has its usefulness and limitations in different clinical situations. Although none can be considered as a single gold standard in clinical practice, several techniques have been developed to give the more reliable results. Invasive tests are performed via endoscopic biopsy specimens and these tests include histology, culture, rapid urease test as well as molecular methods. Developments of endoscopic equipment also contribute to the real-time diagnosis of H. pylori during endoscopy. Urea breathing test and stool antigen test are most widely used non-invasive tests, whereas serology is useful in screening and epidemiological studies. Molecular methods have been used in variable specimens other than gastric mucosa. More than detection of H. pylori infection, several tests are introduced into the evaluation of virulence factors and antibiotic sensitivity of H. pylori, as well as screening precancerous lesions and gastric cancer. The aim of this article is to review the current options and novel developments of diagnostic tests and their applications in different clinical conditions or for specific purposes.

Indexed as

Antibodies, BacterialAntigens, BacterialBacteriological TechniquesBiomarkersBiopsyBreath TestsEndoscopy, GastrointestinalFecesHelicobacter InfectionsHelicobacter pyloriHumansMolecular Diagnostic TechniquesPredictive Value of TestsPrognosisReproducibility of ResultsSerologic TestsAntibodies, BacterialAntigens, BacterialBiomarkersBleedingDiagnosisEradicationGastrectomyHelicobacter pyloriInvasiveNoninvasiveOral specimen

Identifiers

PMID26523098
PMCPMC4616200
OpenAlexW2412375869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.