Evidence map›Paper›PMID 26522783›Full record

ArticleAtencion primaria

[Prevalence of non-vaccinable high risk genotypes of human papillomavirus in the Early Detection of Cervical Cancer Program in Cantabria].

María Paz-Zulueta, Ana Fernández-Feito, Marina Amparán Ruiz, Asunción Azofra Olave, Yolanda Martín Seco, Sonia Ojugas Zabala, Aurora Otero García, Carmen Royano Rasines, Raquel Sarabia-Lavín, Blanca Torres Manrique and 1 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Atencion primaria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

María Paz-ZuluetaDepartamento de Enfermería, Universidad de Cantabria, Cantabria, España. Electronic address: maria.paz@unican.es.
Ana Fernández-FeitoÁrea de Enfermería, Facultad de Medicina y Ciencias de la Salud, Universidad de Oviedo, Asturias, España.
Marina Amparán RuizGerencia de Atención Primaria, Servicio Cántabro de Salud, Cantabria, España.
Asunción Azofra OlaveGerencia de Atención Primaria, Servicio Cántabro de Salud, Cantabria, España.
Yolanda Martín SecoGerencia de Atención Primaria, Servicio Cántabro de Salud, Cantabria, España.
Sonia Ojugas ZabalaGerencia de Atención Primaria, Servicio Cántabro de Salud, Cantabria, España.
Aurora Otero GarcíaGerencia de Atención Primaria, Servicio Cántabro de Salud, Cantabria, España.
Carmen Royano RasinesGerencia de Atención Primaria, Servicio Cántabro de Salud, Cantabria, España.
Raquel Sarabia-LavínDepartamento de Enfermería, Universidad de Cantabria, Cantabria, España.
Blanca Torres ManriqueDepartamento de Enfermería, Universidad de Cantabria, Cantabria, España.
Miguel Santibáñez MargüelloDepartamento de Ciencias Médicas y Quirúrgicas, Universidad de Cantabria-IDIVAL, Cantabria, España.
Servicio Cántabro de Salud · ESUniversidad de Cantabria · ESInstituto de Investigación Marqués de Valdecilla · ESUniversidad de Oviedo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate the prevalence of infection with non-vaccinable high risk genotypes of human papillomavirus (HPV).

designCross-sectional study. LOCATION: Seven randomly selected health centres in Cantabria (Northern Spain).

participantsAll women with an evaluable vaginal smear (n=3,359) between 2010 and 2011. MAIN MEASURES: The variables collected were cytological diagnosis, PCR results, and family planning method. The vaginal smear results were classified with the Bethesda system. The classification by Muñoz et al. was used for typing as oncogenic risk HPV. Proportions and odds ratio (OR) were estimated with corresponding confidence intervals at 95% (95% CI).

resultsThe prevalence of HPV infection was 2.71% (95% CI: 2.15 to 3.27). The prevalence of high oncogenic risk HPV genotypes was 2.26%; (95% CI: 1.75 to 2.78). The most frequent genotype was 16 (28.89%). More than half of the women were positive for one of the non-vaccinable high risk genotypes: 51 (18.89%) and 58 (13.33%) and 68 (12.22%) or 31 (11.11%). At least two non-vaccinable high-risk genotypes co-existed in 23.33% of women. Younger women (≤30 years) had twice the risk of any HPV infection: OR 2.01 (95% CI: 1.02 to 3.96); and were twice as likely to use condoms compared to hormonal contraceptives, OR 2.09 (95% CI: 1.64 to 2.67).

conclusionsAccording to the high percentage of non-vaccinable high oncogenic risk HPV types, there should be a re-think of the prevention strategy in the population, who may have a false sense of protection.

Indexed as

Early Detection of CancerAdultCross-Sectional StudiesFemaleGenotypeHumansPapillomaviridaePapillomavirus InfectionsRisk AssessmentSpainUterine Cervical NeoplasmsDetección precoz del cáncerEarly detection of cancerFrotis vaginal.Infecciones por papilomavirusNeoplasias del cuello uterinoPapillomavirus infectionsPapillomavirus vaccinesUterine cervical neoplasmsVacunas contra papilomavirusVaginal smears.

Identifiers

PMID26522783
PMCPMC6877849
OpenAlexW1862998083

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.