Evidence map›Paper›PMID 26522730›Full record

ArticleTrends in ecology & evolution2015

An Individual-Centered Framework For Unravelling Genotype-Phenotype Interactions.

Michel Baguette, Delphine Legrand, Virginie M Stevens

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in ecology & evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Michel BaguetteStation d'Ecologie Expérimentale, CNRS USR 2936, F-09200 Moulis, France; Muséum National d'Histoire Naturelle, UMR 7205 ISYEB, F-75005, Paris, France. Electronic address: baguette@mnhn.fr.
Delphine LegrandStation d'Ecologie Expérimentale, CNRS USR 2936, F-09200 Moulis, France; Earth and Life Institute, UCL BRC, B-1348, Louvain-la-Neuve, Belgium.
Virginie M StevensStation d'Ecologie Expérimentale, CNRS USR 2936, F-09200 Moulis, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new framework in which the multiple levels of molecular variations contribute to phenotypic variations in a complex, nonlinear and interactive way, challenges the hierarchical nature of the relationships between the genotypic and phenotypic spaces. This individual-centered framework provides new insights on the evolutionary mechanisms involved in the production of phenotypes. We propose to move this research agenda forward by combining selection experiments and functional genetics.

Indexed as

Data Interpretation, StatisticalGenetic VariationGenotypeModels, BiologicalPhenotypeHumansInheritance PatternsSystems BiologyepigenomeGenomemolecular pedigree of evolutionary changesphenomeproteomesyndrome

Identifiers

PMID26522730
OpenAlexW1890622798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.