ArticleNature communications2015
Two-dimensional single-cell patterning with one cell per well driven by surface acoustic waves.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 177 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
177 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- Passive Metasurface Tweezers for Multi-Scale Orbital Transport and Trapping on Elastic Plates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Prototissues: Assembly strategies, collective behaviors, and emerging applications.Bioactive materials · 2026Review
- Space-time acoustofluidic tweezers for dynamic and selective manipulation of microparticles.Science advances · 2026Article
- Acoustofluidic Biosensors.Micromachines · 2026Review
- Surface Acoustic Wave Devices: New Mechanisms, Enabling Techniques, and Application Frontiers.Micromachines · 2026Review
- Unconventional bioprinting modalities for advanced tissue biofabrication.Biomaterials · 2026Review
- Optoelectronic Tweezers for Single-Cell Research: Principles, Applications, and Prospects.Cyborg and bionic systems (Washington, D.C.) · 2026Review
- On-chip phased interdigital metamaterials enable versatile manipulation of surface acoustic waves, microfluids, and micro/nano-objects.Nature communications · 2025Article
- Self-Regulated Selective Surface Coating Enables Confinement of Adherent Cells in Closed Microfluidic Arrays.Analytical chemistry · 2025Article
- Acoustofluidic system for targeted antibody removal in transplantation: Enabling small-volume therapeutic apheresis.Science advances · 2025Article
- Coupling Agents in Acoustofluidics: Mechanisms, Materials, and Applications.Micromachines · 2025Review
- Acoustofluidic bioassembly induced morphogenesis for therapeutic tissue fabrication.Nature communications · 2025Article
- Topological acoustofluidics.Nature materials · 2025Article
- Coalescence of multiple pairs of levitated droplets using dual-side phased arrays.Ultrasonics sonochemistry · 2025Article
- Acoustofluidics-Based Intracellular Nanoparticle Delivery.Engineering (Beijing, China) · 2025Article
- Large-scale acoustic single cell trapping and selective releasing.Lab on a chip · 2025Article
- Improved acoustic holograms using simulated annealing.Biomicrofluidics · 2025Article
- High-Performance and Environmentally-Friendly Bulk-Wave-Acoustofluidic Devices Driven by Lead-Free Piezoelectric Materials.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Improvement of cellular pattern organization and clarity through centrifugal force.Biomedical materials (Bristol, England) · 2025Article
117 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In single-cell analysis, cellular activity and parameters are assayed on an individual, rather than population-average basis. Essential to observing the activity of these cells over time is the ability to trap, pattern and retain them, for which previous single-cell-patterning work has principally made use of mechanical methods. While successful as a long-term cell-patterning strategy, these devices remain essentially single use. Here we introduce a new method for the patterning of multiple spatially separated single particles and cells using high-frequency acoustic fields with one cell per acoustic well. We characterize and demonstrate patterning for both a range of particle sizes and the capture and patterning of cells, including human lymphocytes and red blood cells infected by the malarial parasite Plasmodium falciparum. This ability is made possible by a hitherto unexplored regime where the acoustic wavelength is on the same order as the cell dimensions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.