ArticleNature communications2015
High-throughput 3D tracking of bacteria on a standard phase contrast microscope.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
What it found
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Who cites it
81 citing papers in PubMed.
- Cell-body curvature reduces stall frequency to enhance Vibrio cholerae swimming and chemotaxis through hydrogels.Communications biology · 2026Article
- Precise 3D Tracking of Highly Non-Planar Eukaryotic Flagellar Beating Patterns Using Digital Holographic Microscopy.Small methods · 2026Article
- Spontaneous switching in a protein signalling array reveals near-critical cooperativity.Nature physics · 2026Article
- Cell-body curvature modulates stall frequency to enhancebioRxiv : the preprint server for biology · 2026Article
- Altering chemotaxis as a strategy to enhance the foraging range of motility-restricted bacteria.Communications biology · 2026Article
- Single-array measurements reveal non-uniform, mosaic-like chemosensory arrays in bacteria.Nature communications · 2025Article
- Single camera estimation of microswimmer depth with a convolutional network.Journal of the Royal Society, Interface · 2025Article
- Bacteria Optimize Tumble Bias to Strategically Navigate Surface Constraints.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Spatio-genetically coordinated TPR domain-containing proteins modulate c-di-GMP signaling in Vibrio vulnificus.PLoS pathogens · 2025Article
- Run-and-tumble dynamics ofJournal of the Royal Society, Interface · 2025Article
- The 2025 motile active matter roadmap.Journal of physics. Condensed matter : an Institute of Physics journal · 2025Review
- Decoding Bacterial Motility: From Swimming States to Patterns and Chemotactic Strategies.Biomolecules · 2025Review
- Speed-dependent bacterial surface swimming.Applied and environmental microbiology · 2024Article
- Methods and Measures for Investigating Microscale Motility.Integrative and comparative biology · 2023Review
- Multiflagellarity leads to the size-independent swimming speed of peritrichous bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- RACK1 promotesiScience · 2023Article
- Physiological adaptation in flagellar architecture improvesProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Three-dimensional close-to-substrate trajectories of magnetic microparticles in dynamically changing magnetic field landscapes.Scientific reports · 2022Article
- Real-time monitoring of the dynamics and interactions of bacteria and the early-stage formation of biofilms.Scientific reports · 2022Article
- Rapid Detection of Urinary Tract Infection in 10 min by Tracking Multiple Phenotypic Features in a 30 s Large-Volume Scattering Video of Urine Microscopy.ACS sensors · 2022Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteria employ diverse motility patterns in traversing complex three-dimensional (3D) natural habitats. 2D microscopy misses crucial features of 3D behaviour, but the applicability of existing 3D tracking techniques is constrained by their performance or ease of use. Here we present a simple, broadly applicable, high-throughput 3D bacterial tracking method for use in standard phase contrast microscopy. Bacteria are localized at micron-scale resolution over a range of 350 × 300 × 200 μm by maximizing image cross-correlations between their observed diffraction patterns and a reference library. We demonstrate the applicability of our technique to a range of bacterial species and exploit its high throughput to expose hidden contributions of bacterial individuality to population-level variability in motile behaviour. The simplicity of this powerful new tool for bacterial motility research renders 3D tracking accessible to a wider community and paves the way for investigations of bacterial motility in complex 3D environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.