ArticleThe Journal of veterinary medical science2016
A new insertion/deletion fragment polymorphism of inhibin-α gene associated with follicular cysts in Large White sows.
Article in The Journal of veterinary medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 14 citations in OpenAlex.
- Review
- Candidate genes associated with reproductive traits in rabbits.Tropical animal health and production · 2024Review
- Association betweenPeerJ · 2023Article
- Structural variants and tandem repeats in the founder individuals of four FBMC genomics · 2022Article
- Effects of Inhibin A on Apoptosis and Proliferation of Bovine Granulosa Cells.Animals : an open access journal from MDPI · 2020Article
- Analysis of Expression and Single Nucleotide Polymorphisms ofBioMed research international · 2019Article
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Authors and funding
8 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Ovarian follicular cysts are anovulatory follicular structures that lead to infertility. Hormones play key roles in the formation and persistence of cysts. Inhibins are heterodimeric gonadal glycoprotein hormones that belong to the transforming growth factor-β superfamily. These hormones suppress the secretion of follicle-stimulating hormone. In this report, partial fragment of inhibin-α (INHA) subunit gene of Large White pig was detected from the genomic DNA by polymerase chain reaction. The sequence showed a 283 bp fragment insertion/deletion (I/D) polymorphism in INHA subunit gene. A total of 49 Large White sows with cystic follicles and 152 normal sows were screened for this polymorphism. The relationship of INHA I/D polymorphisms with follicular cysts was investigated. The distribution of I/D was significantly different between cystic and normal sows, thereby suggesting that the INHA subunit gene might be a potential biological marker for breeding programs in pig.
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