Evidence map›Paper›PMID 26520931›Full record

ArticleVeterinary microbiology2015

Molecular and antigenic characterization of bovine Coronavirus circulating in Argentinean cattle during 1994-2010.

M Bok, S Miño, D Rodriguez, A Badaracco, I Nuñes, S P Souza, G Bilbao, E Louge Uriarte, R Galarza, C Vega and 3 more

Open access · greenAbstract read
In one paragraph

Article in Veterinary microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Evaluating the presence of bovine coronavirus in diarrheic calves in Lahore, Punjab, Pakistan: a food security risk.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  15. Assessment of Influential Factors for Scours Associated withAnimals : an open access journal from MDPI · 2021
    Article
  16. Article
  17. Review
  18. Review
  19. Bovine Coronavirus and the Associated Diseases.Frontiers in veterinary science · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

M BokVirology Institute, CICVyA, National Institute of Agricultural Technology (INTA), Buenos Aires, Argentina.
S MiñoVirology Institute, CICVyA, National Institute of Agricultural Technology (INTA), Buenos Aires, Argentina; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, The Chinese Academy of Agriculture Sciences, Harbin, 150001 Heilongjiang, China.
D RodriguezVirology Institute, CICVyA, National Institute of Agricultural Technology (INTA), Buenos Aires, Argentina.
A BadaraccoVirology Institute, CICVyA, National Institute of Agricultural Technology (INTA), Buenos Aires, Argentina.
I NuñesDepartment of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, Brazil.
S P SouzaDepartment of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, Brazil.
G BilbaoLaboratory of Animal Health, EEA INTA- Balcarce, Buenos Aires, Argentina.
E Louge UriarteVeterinary College, UNCPBA, Tandil, Buenos Aires, Argentina.
R GalarzaEEA, INTA Rafaela, Santa Fe, Argentina.
C VegaVirology Institute, CICVyA, National Institute of Agricultural Technology (INTA), Buenos Aires, Argentina.
A OdeonLaboratory of Animal Health, EEA INTA- Balcarce, Buenos Aires, Argentina.
L J SaifFood Animal Health Research Program, The Ohio State University, Wooster, OH, USA.
V ParreñoVirology Institute, CICVyA, National Institute of Agricultural Technology (INTA), Buenos Aires, Argentina. Electronic address: parreno.viviana@inta.gob.ar.
National Agricultural Technology Institute · ARUniversidade de São Paulo · BRCentro Científico Tecnológico - Tandil · ARHarbin Veterinary Research Institute · CNThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine coronavirus (BCoV) is an important viral pathogen associated with neonatal calf diarrhea. Our aim was to investigate the incidence of BCoV in diarrhea outbreaks in beef and dairy herds from Argentina during 1994-2010. A total of 5.365 fecal samples from diarrheic calves were screened for BCoV diagnosis by ELISA. The virus was detected in 1.71% (92/5365) of the samples corresponding to 5.95% (63/1058) of the diarrhea cases in 239 beef and 324 dairy farms. The detection rate of BCoV was significantly higher in dairy than in beef herds: 12.13% (29/239) vs. 4.32% (14/324) respectively. Phylogenetic analysis of the hypervariable S1 region of seven representative samples (from different husbandry systems, farm locations and years of sampling) indicated that BCoV strains circulating in Argentinean beef and dairy herds formed a cluster distinct from other geographical regions. Interestingly, Argentinean strains are distantly related (at both the nucleotide and amino acid levels) with the Mebus historic reference BCoV strain included in the vaccines currently available in Argentina. However, Mebus-induced antibodies were capable of neutralizing the BCoV Arg95, a field strain adapted to grow in vitro, and vice versa, indicating that both strains belong to the same CoV serotype reported in cattle. This work represents the first large survey describing BCoV circulation in Argentinean cattle.

Indexed as

PhylogenyAnimalsAntigens, ViralArgentinaBase SequenceCattleCattle DiseasesCoronavirus, BovineCoronavirus InfectionsDairyingDisease OutbreaksDNA, ViralFecesFemaleMaleMolecular Sequence DataAntigens, ViralDNA, ViralCoronavirusCross-protectionNeonatal calf diarrhea

Identifiers

PMID26520931
PMCPMC7185509
OpenAlexW1888074064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.